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J-14

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3611544

J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 uM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin leading to cytotoxicity and cancer cell death. More details

$220 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
J-14, Biochemical
Full Product Name
J-14
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
517.04
Suitability
DMSO: 260mg/mL (502.86mM) Need ultrasonic
Target
Other Targets
Receptor
sulfiredoxin
SMILES
OC(=O)c1ccc(CSc2nc(cc(n2)-c2ccccc2)N2CCN(CC2)c2ccccc2Cl)cc1
Molecular Formula
C28H25ClN4O2S
CAS Number
1043854-13-2

Product Categories/Family for J-14 biochemical

Others

Structure of J-14 biochemical

J-14 Biochemical – Cat# MBS3611544

Product References and Citations for J-14 biochemical

1.Kim H et al. Sulfiredoxin inhibitor induces preferential death of cancer cells through reactive oxygen species-mediated mitochondrial damage. Free Radic Biol Med. 2016 Feb; 91:264-74.

Other Notes

Small volumes of J-14 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for J-14 purchase

MBS3611544 is a biochemical targeting J-14.
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