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Growth Differentiation Factor 11 (GDF11) ELISA Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS036729

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of GDF11 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Growth Differentiation Factor 11 (GDF11), ELISA Kit
Full Product Name
Mouse Growth Differentiation Factor 11 ELISA Kit
Product Gene Name
GDF11 elisa kit
Species Reactivity
Mouse
Assay Type
Sandwich
Samples
Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Detection Range
62.5 pg/ml - 2000 pg/ml.
Sensitivity
10 pg/ml.
Specificity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Preparation and Storage
Store all reagents at 2-8 degree C
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
Intra-assay Precision
Intra-assay CV (%) is less than 15%.
Molecular Weight
45,091 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (56137064..56146665). Location: 12q13.2
OMIM
603936
3D Structure
ModBase 3D Structure for O95390

Other Notes

Small volumes of GDF11 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GDF11 purchase

MBS036729 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Growth Differentiation Factor 11 (GDF11) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GDF11. The ELISA analytical biochemical technique of the MBS036729 kit is based on GDF11 antibody-GDF11 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GDF11 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GDF11. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GDF11. It may not necessarily be applicable to this product.

NCBI GI #
5031613
NCBI GeneID
10220
NCBI Accession #
NP_005802.1
UniProt Primary Accession #
O95390
UniProt Secondary Accession #
Q9UID1; Q9UID2
UniProt Related Accession #
O95390
GenBank Nucleotide #
NM_005811.3
NCBI Official Full Name
growth/differentiation factor 11
NCBI Official Synonym Full Names
growth differentiation factor 11
NCBI Official Symbol
GDF11
NCBI Official Synonym Symbols
BMP11; BMP-11
UniProt Protein Name
Growth/differentiation factor 11
UniProt Synonym Protein Names
Bone morphogenetic protein 11
Protein Family
Growth/differentiation factor
UniProt Gene Name
GDF11
UniProt Synonym Gene Names
BMP11; GDF-11; BMP-11
UniProt Entry Name
GDF11_HUMAN
NCBI Protein Information
growth/differentiation factor 11; GDF-11; bone morphogenetic protein 11

NCBI Summary for GDF11

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development. [provided by RefSeq, Jul 2008]
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UniProt Comments for GDF11

GDF11: Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. Belongs to the TGF-beta family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12q13.2

Cellular Component: extracellular space

Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: nervous system development; cell maturation; palate development; regulation of apoptosis; negative regulation of cell proliferation; negative regulation of cell differentiation; camera-type eye morphogenesis; spinal cord anterior/posterior patterning; ureteric bud development; regulation of MAPKKK cascade; pancreas development; mesoderm development; cell development; skeletal development; metanephros development; growth
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Research Articles on GDF11

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GDF11 elisa kit

 Reference Product  PubMed Publications
 PCSK5 elisa kit  >3 publications with GDF11 and PCSK5
 WFIKKN1 elisa kit  >3 publications with GDF11 and WFIKKN1
 ACVR2B elisa kit  >3 publications with GDF11 and ACVR2B
 WIF1 elisa kit  >1 publications with GDF11 and WIF1
 CDKN1A elisa kit  >1 publications with GDF11 and CDKN1A
 MAFA elisa kit  >1 publications with GDF11 and MAFA
 FOXG1 elisa kit  >1 publications with GDF11 and FOXG1
 ACVR1B elisa kit  >1 publications with GDF11 and ACVR1B
 ATOH7 elisa kit  >1 publications with GDF11 and ATOH7

Diseases associated with GDF11 elisa kit

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >7 publications with GDF11 and Congenital Abnormalities
 Kidney Diseases Antibodies  >3 publications with GDF11 and Kidney Diseases
 Disease Models, Animal Antibodies  >2 publications with GDF11 and Disease Models, Animal
 Insulin Resistance Antibodies  >1 publications with GDF11 and Insulin Resistance
 Neoplasm Metastasis Antibodies  >1 publications with GDF11 and Neoplasm Metastasis
 Fatty Liver Antibodies  >1 publications with GDF11 and Fatty Liver
 Urogenital Abnormalities Antibodies  >1 publications with GDF11 and Urogenital Abnormalities
 Necrosis Antibodies  >1 publications with GDF11 and Necrosis

Organs/Tissues associated with GDF11 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >60 publications with GDF11 and Bone
 Muscle Antibodies  >20 publications with GDF11 and Muscle
 Embryonic Tissue Antibodies  >16 publications with GDF11 and Embryonic Tissue
 Nerve Antibodies  >11 publications with GDF11 and Nerve
 Kidney Antibodies  >8 publications with GDF11 and Kidney
 Heart Antibodies  >6 publications with GDF11 and Heart
 Eye Antibodies  >6 publications with GDF11 and Eye
 Blood Antibodies  >5 publications with GDF11 and Blood
 Mouth Antibodies  >5 publications with GDF11 and Mouth
 Pancreas Antibodies  >5 publications with GDF11 and Pancreas
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