Insulin Like Growth Factor Binding Protein 1 (IGFBP1) ELISA Kit for Rat

Name: Rat IGFBP1 ELISA Kit; Insulin Like Growth Factor Binding Protein 1; MyBioSource
Brand: MyBioSource
SKU: MBS036949
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS036949

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of IGFBP1 (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates,… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Insulin Like Growth Factor Binding Protein 1 (IGFBP1), ELISA Kit

Full Product Name

Rat Insulin Like Growth Factor Binding Protein 1 ELISA Kit

Product Gene Name

IGFBP1 elisa kit

Species Reactivity

Rat

Assay Type

Sandwich

Samples

Undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

Detection Range

15.6 ng/ml - 500 ng/ml.

Sensitivity

2.0 ng/ml.

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

29,570 Da

Chromosome Location

Chromosome: 11; NC_000077.6 (7197787..7202546). Location: 11 A1; 11 4.75 cM

3D Structure

ModBase 3D Structure for P47876

Other Notes

Small volumes of IGFBP1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IGFBP1 purchase

MBS036949 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Insulin Like Growth Factor Binding Protein 1 (IGFBP1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IGFBP1. The ELISA analytical biochemical technique of the MBS036949 kit is based on IGFBP1 antibody-IGFBP1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IGFBP1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IGFBP1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for IGFBP1. It may not necessarily be applicable to this product.

NCBI GI #

160358847

NCBI GeneID

16006

NCBI Accession #

NP_032367.3

UniProt Primary Accession #

P47876

UniProt Secondary Accession #

Q5SVY8; Q61732

UniProt Related Accession #

P47876

GenBank Nucleotide #

NM_008341.4

NCBI Official Full Name

insulin-like growth factor-binding protein 1

NCBI Official Synonym Full Names

insulin-like growth factor binding protein 1

NCBI Official Symbol

Igfbp1

UniProt Protein Name

Insulin-like growth factor-binding protein 1

Protein Family

Insulin-like growth factor-binding protein

UniProt Gene Name

Igfbp1

UniProt Synonym Gene Names

Igfbp-1; IBP-1; IGF-binding protein 1; IGFBP-1

UniProt Entry Name

IBP1_MOUSE

NCBI Protein Information

insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1 PRECURSOR (IGFBP-1) (IBP-1) (IGF-BINDING PROTEIN 1)

UniProt Comments for IGFBP1

IGFBP1: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; extracellular region

Molecular Function: insulin-like growth factor binding; insulin-like growth factor I binding; growth factor binding; insulin-like growth factor II binding

Biological Process: regulation of insulin-like growth factor receptor signaling pathway; regulation of cell growth

Research Articles on IGFBP1

1. During the two week starvation period, both the levels of plasma IGF-1 and IGFBP-1 decreased.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IGFBP1 elisa kit

Reference Product	PubMed Publications
Igf1r elisa kit	>100 publications with IGFBP1 and Igf1r
Igf1 elisa kit	>60 publications with IGFBP1 and Igf1
Prl elisa kit	>51 publications with IGFBP1 and Prl
Igf2 elisa kit	>25 publications with IGFBP1 and Igf2
Egf elisa kit	>22 publications with IGFBP1 and Egf
Il6 elisa kit	>10 publications with IGFBP1 and Il6
Stat3 elisa kit	>6 publications with IGFBP1 and Stat3
Foxo4 elisa kit	>3 publications with IGFBP1 and Foxo4
Atf4 elisa kit	>3 publications with IGFBP1 and Atf4

Pathways associated with IGFBP1 elisa kit

Products by Pathway	Pathway Diagram
Activation Of Genes By ATF4 Pathway antibodies	Activation Of Genes By ATF4 Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Myometrial Relaxation And Contraction Pathways antibodies	Myometrial Relaxation And Contraction Pathways Diagram
PERK Regulated Gene Expression Pathway antibodies	PERK Regulated Gene Expression Pathway Diagram
Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway antibodies	Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway Diagram
Unfolded Protein Response Pathway antibodies	Unfolded Protein Response Pathway Diagram

Diseases associated with IGFBP1 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>379 publications with IGFBP1 and Neoplasms
Liver Diseases Antibodies	>127 publications with IGFBP1 and Liver Diseases
Cardiovascular Diseases Antibodies	>114 publications with IGFBP1 and Cardiovascular Diseases
Disease Models, Animal Antibodies	>85 publications with IGFBP1 and Disease Models, Animal
Kidney Diseases Antibodies	>82 publications with IGFBP1 and Kidney Diseases
Liver Neoplasms Antibodies	>80 publications with IGFBP1 and Liver Neoplasms
Adenocarcinoma Antibodies	>79 publications with IGFBP1 and Adenocarcinoma
Brain Diseases Antibodies	>72 publications with IGFBP1 and Brain Diseases
Necrosis Antibodies	>62 publications with IGFBP1 and Necrosis
Inflammation Antibodies	>59 publications with IGFBP1 and Inflammation

Organs/Tissues associated with IGFBP1 elisa kit

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>429 publications with IGFBP1 and Liver
Kidney Antibodies	>156 publications with IGFBP1 and Kidney
Muscle Antibodies	>144 publications with IGFBP1 and Muscle
Embryonic Tissue Antibodies	>123 publications with IGFBP1 and Embryonic Tissue
Lung Antibodies	>44 publications with IGFBP1 and Lung
Extraembryonic Tissue Antibodies	>8 publications with IGFBP1 and Extraembryonic Tissue
Uncharacterized Tissue Antibodies	>1 publications with IGFBP1 and Uncharacterized Tissue