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Parathyroid Hormone (PTH) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS370271

MBS370271 is an antibody targeting PTH. Also known as Parathyroid Hormone (PTH). Reactive in Human. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Parathyroid Hormone (PTH), Monoclonal Antibody
Full Product Name
Parathyroid Hormone (PTH)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
MRQ-31
Host
Mouse
Species Reactivity
Human
Preparation and Storage
Store at 2 to 8 degree C in the dark.
Molecular Weight
12,861 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (13513601..13517567, complement). Location: 11p15.3-p15.1
OMIM
146200
3D Structure
ModBase 3D Structure for P01270
ISO Certification
Manufactured in an ISO 13485:2016 Certified Laboratory.

Other Notes

Small volumes of anti-PTH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PTH. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
parathyroid hormone preproprotein
NCBI Official Synonym Full Names
parathyroid hormone
NCBI Official Symbol
PTH
NCBI Official Synonym Symbols
PTH1
UniProt Protein Name
Parathyroid hormone
UniProt Synonym Protein Names
Parathormone; Parathyrin
Protein Family
UniProt Gene Name
PTH
UniProt Synonym Gene Names
PTH
UniProt Entry Name
PTHY_HUMAN
NCBI Protein Information
parathyroid hormone; parathyrin; prepro-PTH; parathormone; parathyroid hormone 1; preproparathyroid hormone

NCBI Summary for PTH

The protein encoded by this gene is a hormone secreted by parathyroid cells. This hormone elevates blood Ca2+ level by dissolving the salts in bone and preventing their renal excretion. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH). [provided by RefSeq, Jul 2008]

UniProt Comments for PTH

Function: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. Ref.13

Subunit structure: Interacts with PTH1R (via N-terminal extracellular domain). Ref.19

Subcellular location: Secreted.

Involvement in disease: Familial isolated hypoparathyroidism (FIH) [MIM:146200]: Characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. An autosomal recessive form of FIH also exists.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.20 Ref.21 Ref.22

Sequence similarities: Belongs to the parathyroid hormone family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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