Human APELIN -13 ELISA Kit – Cat# MBS037239

Apelin 13 (APELIN -13) ELISA Kit for Human

Name: Human APELIN -13 ELISA Kit; Apelin 13; MyBioSource
Brand: MyBioSource
SKU: MBS037239
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS037239

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used to determine the level of AP (hereafter termed "analyte") in undiluted original Bovine body fluids and tissue homogenates. This… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Apelin 13 (APELIN -13), ELISA Kit

Full Product Name

Human Apelin 13 ELISA Kit

Product Gene Name

APELIN -13 elisa kit

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Samples

Bovine Body Fluids And Tissue Homogenates

Detection Range

3.12ng/ml-100ng/ml

Sensitivity

1.0ng/ml.

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%

Molecular Weight

42,660 Da

OMIM

600052

3D Structure

ModBase 3D Structure for P35414

Other Notes

Small volumes of APELIN -13 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for APELIN -13 purchase

MBS037239 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Apelin 13 (APELIN -13) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing APELIN -13. The ELISA analytical biochemical technique of the MBS037239 kit is based on APELIN -13 antibody-APELIN -13 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect APELIN -13 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, APELIN -13. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for APELIN -13. It may not necessarily be applicable to this product.

NCBI GI #

4885057

NCBI GeneID

187

NCBI Accession #

NP_005152.1

UniProt Primary Accession #

P35414

UniProt Related Accession #

P35414

GenBank Nucleotide #

NM_005161.4

NCBI Official Full Name

apelin receptor

NCBI Official Synonym Full Names

apelin receptor

NCBI Official Symbol

APLNR

NCBI Official Synonym Symbols

APJ; APJR; HG11; AGTRL1

UniProt Protein Name

Apelin receptor

UniProt Synonym Protein Names

Angiotensin receptor-like 1; G-protein coupled receptor APJ; G-protein coupled receptor HG11

UniProt Gene Name

APLNR

UniProt Synonym Gene Names

AGTRL1; APJ

UniProt Entry Name

APJ_HUMAN

NCBI Protein Information

apelin receptor; APJ receptor; HG11 orphan receptor; APJ (apelin) receptor; angiotensin receptor-like 1; G protein-coupled receptor APJ; G-protein coupled receptor APJ; angiotensin II receptor-like 1; G-protein coupled receptor HG11

NCBI Summary for APELIN -13

This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq, Jul 2009]

UniProt Comments for APELIN -13

AGTRL1: Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 11q12

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; regulation of body fluid levels; heart development; gastrulation

Research Articles on APELIN -13

1. functional role of the apelin--APJ system likely in early gestation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with APELIN -13 elisa kit

Reference Product	PubMed Publications
APLN elisa kit	>163 publications with APELIN -13 and APLN
VEGFA elisa kit	>2 publications with APELIN -13 and VEGFA
POMC elisa kit	>2 publications with APELIN -13 and POMC

Pathways associated with APELIN -13 elisa kit

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Diseases associated with APELIN -13 elisa kit

Disease Name	Pubmed Publications
Heart Diseases Antibodies	>35 publications with APELIN -13 and Heart Diseases
Hypertension Antibodies	>33 publications with APELIN -13 and Hypertension
Disease Models, Animal Antibodies	>19 publications with APELIN -13 and Disease Models, Animal
Nervous System Diseases Antibodies	>13 publications with APELIN -13 and Nervous System Diseases
Hypertrophy Antibodies	>11 publications with APELIN -13 and Hypertrophy
Inflammation Antibodies	>11 publications with APELIN -13 and Inflammation
Neoplasms Antibodies	>9 publications with APELIN -13 and Neoplasms
Kidney Diseases Antibodies	>8 publications with APELIN -13 and Kidney Diseases
Brain Diseases Antibodies	>8 publications with APELIN -13 and Brain Diseases
Lung Diseases Antibodies	>8 publications with APELIN -13 and Lung Diseases

Organs/Tissues associated with APELIN -13 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>91 publications with APELIN -13 and Blood
Heart Antibodies	>67 publications with APELIN -13 and Heart
Brain Antibodies	>40 publications with APELIN -13 and Brain
Kidney Antibodies	>19 publications with APELIN -13 and Kidney
Lung Antibodies	>18 publications with APELIN -13 and Lung
Embryonic Tissue Antibodies	>15 publications with APELIN -13 and Embryonic Tissue
Connective Tissue Antibodies	>13 publications with APELIN -13 and Connective Tissue
Adipose Tissue Antibodies	>12 publications with APELIN -13 and Adipose Tissue
Eye Antibodies	>8 publications with APELIN -13 and Eye
Ovary Antibodies	>6 publications with APELIN -13 and Ovary