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Alpha-1-Antichymotrypsin (a1ACT) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2003816
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MBS2003816 is an antibody targeting a1ACT. Also known as Polyclonal Antibody to Alpha-1-Antichymotrypsin (a1ACT). Reactive in Homo sapiens (Human). Host: Rabbit. More details

$210 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Alpha-1-Antichymotrypsin (a1ACT), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Alpha-1-Antichymotrypsin (a1ACT)
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Homo sapiens (Human)
Form/Format
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
0.5mg/mL (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.

Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: a1ACT (MBS2003816)
Immunogen: a1ACT (MBS2011877)
Matching Pairs
Unconjugated Antibody: a1ACT (MBS2003816)
APC-CY7 Conjugated Antibody: a1ACT (MBS2050476)
OMIM
K01500 mRNA
3D Structure
ModBase 3D Structure for P01011
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Polyclonal antibody preparation
Traits
Liquid
Immunogen
Recombinant a1ACT (Lys235~Arg394) expressed in E.coli (MBS2011877).
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-a1ACT antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-a1ACT antibody
Western blotting: 0.01-2ug/mL;
Immunohistochemistry: 5-20ug/mL;
Optimal working dilutions must be determined by end user.

Immunohistochemistry (IHC) of anti-a1ACT antibody

DAB staining on IHC-P;
Samples: Human Liver Tissue;
Primary Ab: 10ug/ml Rabbit Anti-Human a1ACT Antibody
Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047)
Rabbit Anti-a1ACT Polyclonal Antibody – Cat# MBS2003816

Immunohistochemistry (IHC) of anti-a1ACT antibody

DAB staining on IHC-P;
Samples: Human Kidney Tissue;
Primary Ab: 10ug/ml Rabbit Anti-Human a1ACT Antibody
Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047)
Rabbit Anti-a1ACT Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2003816

Western Blot (WB) of anti-a1ACT antibody

Western Blot;
Samples:
Lane 1: Human Serum;
Lane 2: Human Plasma;
Primary Ab: 0.5ug/ml Rabbit Anti-Human a1ACT Antibody
Second Ab: 0.2ug/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047)
Rabbit Anti-a1ACT Polyclonal Antibody, Western Blot (WB) – Cat# MBS2003816

Other Notes

Small volumes of anti-a1ACT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for a1ACT. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
alpha-1-antichymotrypsin
NCBI Official Synonym Full Names
serpin family A member 3
NCBI Official Symbol
SERPINA3
NCBI Official Synonym Symbols
ACT; AACT; GIG24; GIG25
UniProt Protein Name
Alpha-1-antichymotrypsin
UniProt Synonym Protein Names
Cell growth-inhibiting gene 24/25 protein; Serpin A3
UniProt Gene Name
SERPINA3
UniProt Synonym Gene Names
AACT; ACT
NCBI Protein Information
alpha-1-antichymotrypsin

NCBI Summary for a1ACT

The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008]
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UniProt Comments for a1ACT

Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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Pathways associated with anti-a1ACT antibody

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