CENPE Antibody – Mouse Monoclonal

MBS375006 is an antibody targeting CENPE. Also known as Mouse Anti-CENPE [1H12]. Reactive in Human. Host: Mouse.

CENPE, a novel human centromereassociated protein required for progression from metaphase to anaphase. Yen T.J (Embo J,May 1991) PMID: 2022189 PIASgamma is required for faithful chromosome segregation in human cells. D-az-Mart-nez LA et al. PLoS One. 2006 Dec 20;1:e53 PMID: 17183683 Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function.Schafer-Hales K et al.Mol Cancer Ther. 2007 Apr;6(4):1317-28. ICC/IF(Human)PMID: 17431110 Hu CK et al. Midbody assembly and its regulation during cytokinesis. Mol Biol Cell 23:1024-34 (2012). ICC/IF PMID: 22278743 Serio G et al. Small GTPase Rab5 participates in chromosome congression and regulates localization of the centromere-associated protein CENP-F to kinetochores. Proc Natl Acad Sci U S A 108:17337-42 (2011). IHC (PFA fixed) ; HumanPMID: 21987812 Kim Y et al. Aurora Kinases and Protein Phosphatase 1 Mediate Chromosome Congression through Regulation of CENP-E. Cell 142:444-455 (2010). ICC/IF ; Human PMID: 20691903 Stimpson KM et al. Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes. PLoS Genet 6: (2010). ICC/IF ; Human PMID: 20711355 Townsend K et al. Mediator of DNA damage checkpoint 1 (MDC1) regulates mitotic progression. J Biol Chem 284:33939-48 (2009). ICC/IF ; Human PMID: 19826003 Cheng TS et al. Glycogen synthase kinase 3beta interacts with and phosphorylates the spindle-associated protein astrin. J Biol Chem 283:2454-64 (2008). ICC/IF ; Human PMID: 18055457 Chang P et al. Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function. Nat Cell Biol 7:1133-9 (2005) PMID: 16244666

Small volumes of anti-CENPE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.