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Drosophila FMR1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS375072

MBS375072 is an antibody targeting Drosophila FMR1. Also known as Mouse Anti-Drosophila FMR1 [6A15]. Reactive in Fruit fly (Drosophila melanogaster). Does not react with Human. Host: Mouse. More details

$545 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Drosophila FMR1, Monoclonal Antibody
Full Product Name
Mouse Anti-Drosophila FMR1 [6A15]
Product Synonym Names
Drosophila FMR1 antibody; dFMR antibody; dFMR1 antibody; dFXR antibody; Drosophila fragile X mentalretardation protein antibody; FMRP antibody; Fragile X mental retardation 1 antibody; Fragile X mental retardation1 protein antibody; fragile X mental retardation protein antibody; FRAXA antibody; Protein FMR1antibody
Clonality
Monoclonal
Isotype
IgG1
Clone Number
6A15
Host
Mouse
Species Reactivity
Fruit fly (Drosophila melanogaster). Does not react with Human
Form/Format
Purified antibody (from supernatant) containing PBS 0.1% sodium azide;
Purity/Purification
Protein A
Concentration
1mg/ml (lot specific)
Target Antigen
Drosophila FMR1
Immunogen
His-dFMR1 fusion protein (Drosophilia melanogaster) (C-terminal 580aa).
Myeloma/fusion Partners
SP2/0
Research Areas
Neuroscience; signal transduction
Applications Tested/Suitable for anti-Drosophila FMR1 antibody
Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), ELISA (EIA), Western Blot (WB)
Application Notes for anti-Drosophila FMR1 antibody
Optimal antibody dilution should be determined by titration, however as a guideline try at IP: Use at 25 ug/mg of lysate WB: Use at an assay dependent dilution. Detects a band of approximately 85 kDa (predicted molecular weight: 82 kDa)

Product References and Citations for anti-Drosophila FMR1 antibody

Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein. Wan L (Molecular and Cellular Biology,Nov 2000) PUBMED Callan MA et al. Fragile X Protein is required for inhibition of insulin signaling and regulates glial-dependent neuroblast reactivation in the developing brain. Brain Res 1462:151-61 (2012). ICC/IF ; Fruit fly (Drosophila melanogaster) PUBMED Lim C et al. The novel gene twenty-four defines a critical translational step in the Drosophila clock. Nature 470:399-403 (2011) PUBMED Callan MA et al. Fragile X protein controls neural stem cell proliferation in the Drosophila brain. Hum Mol Genet 19:3068-79 (2010). Fruit fly (Drosophila melanogaster) PUBMED Monzo K et al. Proteomic analysis reveals CCT is a target of Fragile X mental retardation protein regulation in Drosophila. Dev Biol 340:408-18 (2010) PUBMED Kwak JE et al. GLD2 poly(A) polymerase is required for long-term memory. Proc Natl Acad Sci U S A 105:14644-9 (2008). Fruit fly (Drosophila melanogaster) PUBMED Monzo K et al. Fragile X mental retardation protein controls trailer hitch expression and cleavage furrow formation in Drosophila embryos. Proc Natl Acad Sci U S A 103:18160-5 (2006). IP PUBMED

Other Notes

Small volumes of anti-Drosophila FMR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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