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EME1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS375124

MBS375124 is an antibody targeting Eme1. Also known as Mouse Anti-Eme1 [7h2/1]. Reactive in Human. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Eme1, Monoclonal Antibody
Full Product Name
Mouse Anti-Eme1 [7h2/1]
Product Gene Name
Product Synonym Names
6820428D13 antibody; Crossover junction endonuclease EME1 antibody; EC 3.1.22.- antibodyEme1 essential meiotic endonuclease 1 homolog 1 (S. pombe) antibody; EME1, S. pombe, homolog of, 1 antibody; essential meiotic endonuclease 1 homolog 1 (S pombe) antibody; Essential Meiotic Endonuclease 1 Homolog 1 antibody; essential meiotic endonuclease 1 homolog 2 antibody; Essential meiotic endonuclease 1, S. pombe, homolog of, 1 antibody; FLJ31364 antibodyhMMS4 antibodyhomolog of yeast EME1 endonuclease antibody; MGC106543 antibody; MMS4 antibody; MMS4 homolog antibody; MMS4L antibody
Clonality
Monoclonal
Isotype
IgG1
Clone Number
7h2/1
Host
Mouse
Species Reactivity
Human
Form/Format
Purified antibody containing PBS 0.1% sodium azide;
Purity/Purification
Protein A purified
Concentration
0.8mg/ml (lot specific)
Molecular Weight
5,076 Da
Target Antigen
Eme1 (Msm4)
Immunogen
Human Eme1 (60-65Kd)
Myeloma/fusion Partners
Sp2/0 Ag.14
Research Areas
Cell Biology
Applications Tested/Suitable for anti-Eme1 antibody
Western Blot (WB)
Application Notes for anti-Eme1 antibody
Optimal antibody dilution should be determined by titration, however as a guideline use at 1:1000 for western blot

Product References and Citations for anti-Eme1 antibody

Stoepker C et al. SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype. Nat Genet. 2011 Feb;43(2):138-41. doi: 10.1038/ng.751. Epub 2011 Jan 16.WB ; Human PMID: 21240277 Mu+/-oz IM et al. Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair.Mol Cell. 2009 Jul 10;35(1):116-27. doi: 10.1016/j.molcel.2009.06.020.WB ; Human PMID: 19595721 Vigneron A et al. The EGFR-STAT3 oncogenic pathway up-regulates the Eme1 endonuclease to reduce DNA damage after topoisomerase I inhibition.Cancer Res. 2008 Feb 1;68(3):815-25. doi: 10.1158/0008-5472.CAN-07-5115.WB ; Human PMID: 18245483

Other Notes

Small volumes of anti-Eme1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Eme1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
NCBI Official Full Name
EME1, partial
UniProt Protein Name
EME1
UniProt Synonym Protein Names
EME1
UniProt Entry Name
I6M498_KRYMA

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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