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Cytokeratin 13 (KRT13) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS375184

MBS375184 is an antibody targeting KRT13. Also known as Mouse Anti-Cytokeratin 13 [AE8]. Reactive in Mouse, Rabbit, Human. Host: Mouse. More details

$545 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Cytokeratin 13 (KRT13), Monoclonal Antibody
Full Product Name
Mouse Anti-Cytokeratin 13 [AE8]
Product Gene Name
Product Synonym Names
type I cytoskeletal 13 antibody; 47 kDa cytokeratin antibody; CK 13 antibody; CK-13antibody; CK13 antibody; Cytokeratin 13 antibody; Cytokeratin-13 antibody; Cytokeratin13 antibody; K13antibody; K1C13_HUMAN antibody; Ka13 antibody; Keratin 13 antibody; Keratin antibody; keratin type Icytoskeletal 13 antibody; Keratin-13 antibody; Keratin13 antibody; KRT 13 antibody; Krt-1.13 antibody; Krt1-13antibody; KRT13 antibody; MGC161462 antibody; MGC3781 antibody; Type I keratin Ka13 antibody
Clonality
Monoclonal
Isotype
Ig
Clone Number
AE8
Host
Mouse
Species Reactivity
Mouse, Rabbit, Human
Form/Format
Purified antibody containing PBS 0.1% sodium azide;
Purity/Purification
Protein G purified
Concentration
0.7mg/ml (lot specific)
Molecular Weight
45,867 Da
OMIM
148065
3D Structure
ModBase 3D Structure for P13646
Target Antigen
Cytokeratin 13
Immunogen
Rabbit esophageal keratins
Myeloma/fusion Partners
P3 x 63 Ag8 myeloma cells
Research Areas
Cell Biology; Cytokeratins; Cytoskeleton; Cytoskeleton / ECM; Tags Cell Markers
Applications Tested/Suitable for anti-KRT13 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Application Notes for anti-KRT13 antibody
Optimal antibody dilution should be determined by titration, however as guideline try at WB: 1/1000 - 1/3000. Predicted molecular weight: 50 kDa

Immunohistochemistry (IHC) of anti-KRT13 antibody

Mouse Anti-KRT13 Monoclonal Antibody – Cat# MBS375184

Product References and Citations for anti-KRT13 antibody

Expression of hairrelated keratins in a soft epithelium: subpopulations of human and mouse dorsal tongue keratinocytes express keratin markers for hair, skin and esophagealtypes of differentiation. Dhouailly D (Exp Cell Res.,Mar 1998) PMID: 2465162 Parikh N et al. Mouse Tissues that Undergo Neoplastic Progression after K-Ras Activation Are Distinguished by Nuclear Translocation of phospho-Erk1/2 and Robust Tumor Suppressor Responses. Mol Cancer Res 10:845-55 (2012). IHC-P PMID: 22532587 Alameda JP et al. An inactivating CYLD mutation promotes skin tumor progression by conferring enhanced proliferative, survival and angiogenic properties to epidermal cancer cells. Oncogene 29:6522-32 (2010). IHC-P ; Human PMID: 20838385 Moreno-Maldonado R et al. IKKalpha enhances human keratinocyte differentiation and determines the histological variant of epidermal squamous cell carcinomas. Cell Cycle 7:2021-9 (2008). IHC-P ; Human PMID: 18604171 Leedham SJ et al. Individual crypt genetic heterogeneity and the origin of metaplastic glandular epithelium in human Barrett's oesophagus. Gut 57:1041-8 (2008). ICC/IF ; Human PMID: 18305067 Parikh N et al. Isolation and characterization of an immortalized oral keratinocyte cell line of mouse origin. Arch Oral Biol 53:1091-100 (2008) PMID: 18721915 Kimball JR et al. Antimicrobial barrier of an in vitro oral epithelial model. Arch Oral Biol 51:775-83 (2006)PMID:16815238 Wada-Hiraike O et al. Role of estrogen receptor beta in uterine stroma and epithelium: Insights from estrogen receptor beta-/- mice. Proc Natl Acad Sci U S A 103:18350-5 (2006). IHC-P ; Mouse PMID: 17110437

Other Notes

Small volumes of anti-KRT13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KRT13. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
NCBI Official Full Name
cytokeratin 13
UniProt Protein Name
Keratin, type I cytoskeletal 13
UniProt Synonym Protein Names
Cytokeratin-13; CK-13; Keratin-13; K13
Protein Family
UniProt Gene Name
KRT13
UniProt Synonym Gene Names
CK-13; K13
UniProt Entry Name
K1C13_HUMAN

UniProt Comments for KRT13

K13: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. Generally associates with K4

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: intermediate filament cytoskeleton; keratin filament; nucleus

Molecular Function: structural molecule activity

Biological Process: response to radiation; tongue morphogenesis; cytoskeleton organization and biogenesis

Disease: White Sponge Nevus 2
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KRT13 antibody

 Reference Product  PubMed Publications
 KRT7 antibody  >2 publications with KRT13 and KRT7
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