hnRNP L Antibody – Mouse Monoclonal

MBS375189 is an antibody targeting hnRNP L. Also known as Mouse Anti-hnRNP L [4D11]. Reactive in Mouse, Rat, Human, Newt. Host: Mouse.

Peddigari S et al. hnRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotransposition. Nucleic Acids Res 41:575-85 (2013). WB ; Human PUBMED Motta-Mena LB et al. A Disease-associated Polymorphism Alters Splicing of the Human CD45 Phosphatase Gene by Disrupting Combinatorial Repression by Heterogeneous Nuclear Ribonucleoproteins (hnRNPs). J Biol Chem 286:20043-53 (2011). WB ; Human PUBMED Heyd F & Lynch KW Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing. Mol Cell 40:126-37 (2010). WB ; Human PUBMED Wang E & Cambi F Heterogeneous Nuclear Ribonucleoproteins H and F Regulate the Proteolipid Protein/DM20 Ratio by Recruiting U1 Small Nuclear Ribonucleoprotein through a Complex Array of G Runs. J Biol Chem 284:11194-204 (2009). WB PUBMED Jia R et al. Control of the papillomavirus early-to-late switch by differentially expressed SRp20. J Virol 83:167-80 (2009). WB ; Human PUBMED Niu Y et al. Identification of peptides applicable as vaccines for HLA-A26-positive cancer patients. Cancer Sci 100:2167-74 (2009). Flow Cyt ; Human PUBMED Venables JP et al. Multiple and specific mRNA processing targets for the major human hnRNP proteins. Mol Cell Biol 28:6033-43 (2008). WB ; Human PUBMED Melton AA et al. Combinatorial control of signal-induced exon repression by hnRNP L and PSF. Mol Cell Biol 27:6972-84 (2007). WB ; Human PUBMED Szeszel-Fedorowicz W et al. An exonic splicing silencer is involved in the regulated splicing of glucose 6-phosphate dehydrogenase mRNA.J Biol Chem. 2006 Nov 10;281(45):34146-58. Epub 2006 Sep 15. WB ; Human, RatPMID: 16980303 Griffith BN et al. Identification of hnRNPs K, L and A2/B1 as candidate proteins involved in the nutritional regulation of mRNA splicing.Biochim Biophys Acta. 2006 Nov-Dec;1759(11-12):552-61. Epub 2006 Oct 6. WB ; MousePMID: 17095106 Rothrock CR et al. HnRNP L represses exon splicing via a regulated exonic splicing silencer. EMBO J 24:2792-802 (2005) PUBMED A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts. Pinol Roma S, Swanson MS, Gall JG, Dreyfuss G (The Journal of Cell Biology,1989)PUBMED

Small volumes of anti-hnRNP L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.