Mouse Anti-Mad2L1 Monoclonal Antibody – Cat# MBS375206

Mad2L1 Antibody – Mouse Monoclonal

Name: Mad2L1 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS375206
Price: 545 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS375206

MBS375206 is an antibody targeting Mad2L1. Also known as Mouse Anti-Mad2L1 [17D10]. Reactive in Human. Host: Mouse. More details

$545 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Mad2L1, Monoclonal Antibody

Full Product Name

Mouse Anti-Mad2L1 [17D10]

Product Gene Name

anti-Mad2L1 antibody

Product Synonym Names

Homolog of MAD2 S cerevisiae antibody; HsMAD 2 antibody; HsMAD2 antibody; Human mitotic feedback controlprotein Madp2 antibody; MAD 2 antibody; MAD 2A antibody; MAD2 antibody; MAD2 like 1 antibody; MAD2 like protein1 antibody; MAD2 mitotic arrest deficient like 1 antibody; MAD2A antibody; Mitotic arrest deficient like 1antibody; Mitotic arrest deficient yeast homolog antibody; Mitotic arrest deficient yeast homolog like 1antibody; Mitotic spindle assembly checkpoint protein antibody

Clonality

Monoclonal

Isotype

IgG1

Clone Number

17D10

Host

Mouse

Species Reactivity

Human

Form/Format

Purified antibody (from supernatant) containing PBS 0.1% sodium azide

Purity/Purification

Protein A

Concentration

1mg/ml (lot specific)

Specificity

Western blot with a variety of human cell lines (eg HeLa) confirms that the antibody is specific for Mad2L1.

Target Antigen

Mad2L1

Immunogen

Recombinant human Mad2L1

Research Areas

Cell Biology; Cell Division; Nucleus; RNA binding; Spindle; Subcellular Markers; Tags Cell Markers

Applications Tested/Suitable for anti-Mad2L1 antibody

Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), Western Blot (WB)

Application Notes for anti-Mad2L1 antibody

Optimal antibody dilution should be determined by titration, however as a guideline try; WB: Use a concentration of 2 ug/ml. Detects a band of approximately 25 kDa (predicted molecular weight: 24.6 kDa). IP: Use a concentration of 5 ug/ml

Product References and Citations for anti-Mad2L1 antibody

Gysin S et al. Analysis of mRNA profiles after MEK1/2 inhibition in human pancreatic cancer cell lines reveals pathways involved in drug sensitivity. Mol Cancer Res 10:1607-19 (2012).WB ; HumanPUBMED Burum-Auensen E et al. Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors.J Carcinog. 2010 Mar 4;9:1. doi: 10.4103/1477-3163.60358. IHC WB ; HumanPMID: 20411023 Ingemarsdotter C et al. The DNA damage response to non-replicating adeno-associated virus: Centriole overduplication and mitotic catastrophe independent of the spindle checkpoint.Virology. 2010 May 10;400(2):271-86. doi: 10.1016/j.virol.2010.02.003. Epub 2010 Mar 2.PWB ; Human PMID: 20199789 Sarfraz S et al. Modulations of cell cycle checkpoints during HCV associated disease. BMC Infect Dis 9:125 (2009). WB ; Human PUBMED Burum-Auensen E et al. Spindle proteins Aurora A and BUB1B, but not Mad2, are aberrantly expressed in dysplastic mucosa of patients with longstanding ulcerative colitis.J Clin Pathol. 2007 Dec;60(12):1403-8. Epub 2007 Feb 23. IHC ; Human PMID: 17322345 Burum-Auensen E et al. Subcellular localization of the spindle proteins Aurora A, Mad2, and BUBR1 assessed by immunohistochemistry.J Histochem Cytochem. 2007 May;55(5):477-86. Epub 2007 Jan 22.IHC WB ; Human PMID: 17242465 Wise SS et al. Chronic exposure to particulate chromate induces spindle assembly checkpoint bypass in human lung cells. Chem Res Toxicol 19:1492-8 (2006). WB ; Human PUBMED

Other Notes

Small volumes of anti-Mad2L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Mad2L1. It may not necessarily be applicable to this product.

Protein Family

Mitotic spindle assembly checkpoint protein

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.