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CD41 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS375350

MBS375350 is an antibody targeting CD41. Also known as Mouse anti CD41 [M148]: Fluorescein. Reactive in Human. Host: Mouse. More details

$680 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD41, Monoclonal Antibody
Full Product Name
Mouse anti CD41 [M148]: Fluorescein
Product Gene Name
Product Synonym Names
CD41; CD41B; GP2B; GPalpha IIb; GPIIb; GTA; HPA3; integrin alpha 2b; Integrin alpha-IIb; Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); ITA2B; ITGA2B; ITGAB; platelet fibrinogen receptor, alpha subunit; Platelet membrane glycoprotein IIb; platelet-specific antigen BAK
Clonality
Monoclonal
Isotype
IgG1
Clone Number
M148
Host
Mouse
Species Reactivity
Human
Form/Format
Purified IgG conjugated to Fluorescein, supplied in Phosphate buffered saline (PBS) containing 0.09% Sodium azide
Purity/Purification
Purified on protein A from tissue culture supernatant.
Concentration
1mg/ml (lot specific)
Specificity
This antibody recognises integrin alpha 2b, a 110-130 kDa transmembrane protein that is also known as CD41. CD41 associates with the integrin CD61 to form the CD41/CD61 (GPIIb/IIIa) heterodimer, a fibronectin receptor expressed in platelets. The antibody M148 binds to some medulloblastoma and neuroblastoma cells and rhabdomyosarcoma and certain other solid tumours. No binding is observed to marrow constituents other than platelets and megakaryocytes. The antibody M148 prevents aggregation of platelets.
Matching Pairs
Unconjugated Azide Free Antibody: CD41 Clone #M148 (MBS375283)
FITC Conjugated Antibody: CD41 Clone #M148 (MBS375350)
Molecular Weight
20,050 Da
Target Antigen
CD41
Immunogen
Homogenized human medulloblastoma tissue.
Myeloma/fusion Partners
Cells from immunized Balb/c mice were fused with the P3X63Ag8.653 myeloma cell line
Research Areas
Cell adhesion; Immune response
Applications Tested/Suitable for anti-CD41 antibody
Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-CD41 antibody
Optimal antibody dilution should be determined by titration

Product References and Citations for anti-CD41 antibody

Jones D, et al. A monoclonal antibody binding to human medulloblastoma cells and to the platelet glycoprotein IIB-IIIA complex. Br J Haematol. 1984.57(4):621-31. PMID:6234927 http://www.ncbi.nlm.nih.gov/pubmed/6234927

Other Notes

Small volumes of anti-CD41 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD41. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
NCBI Official Full Name
CD41 antigen, partial
UniProt Protein Name
CD41 antigen
UniProt Synonym Protein Names
CD41 antigen
Protein Family
UniProt Gene Name
CD41
UniProt Entry Name
F7J059_TURTR

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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