Horse CASPASE-6 ELISA Kit – Cat# MBS037671

Caspase 6 (CASPASE-6) ELISA Kit for Horse

Name: Horse CASPASE-6 ELISA Kit; Caspase 6; MyBioSource
Brand: MyBioSource
SKU: MBS037671
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS037671

MBS037671 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Caspase 6 (CASPASE-6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Caspase 6 (CASPASE-6), ELISA Kit

Full Product Name

Horse Caspase 6 ELISA Kit

Product Gene Name

CASPASE-6 elisa kit

Species Reactivity

Horse

Assay Type

Sandwich

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

31,595 Da

Chromosome Location

Chromosome: 3; NC_000069.6 (129901425..129914102). Location: 3; 3 H1

3D Structure

ModBase 3D Structure for O08738

Other Notes

Small volumes of CASPASE-6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CASPASE-6. It may not necessarily be applicable to this product.

NCBI GI #

157951736

NCBI GeneID

12368

NCBI Accession #

NP_033941.3

UniProt Primary Accession #

O08738

UniProt Related Accession #

O08738

GenBank Nucleotide #

NM_009811.3

NCBI Official Full Name

caspase-6

NCBI Official Synonym Full Names

caspase 6

NCBI Official Symbol

Casp6

NCBI Official Synonym Symbols

Mch2; mCASP-6

UniProt Protein Name

Caspase-6

UniProt Synonym Protein Names

Apoptotic protease Mch-2

Protein Family

Caspase

UniProt Gene Name

Casp6

UniProt Synonym Gene Names

CASP-6

UniProt Entry Name

CASP6_MOUSE

NCBI Protein Information

caspase-6; CASP-6; apoptotic protease Mch-2

NCBI Summary for CASPASE-6

This gene encodes a member of the cysteine proteases that plays important roles in regulating apoptosis and neurodegeneration. The encoded protein is involved in the transmission of pain and axonal degeneration. Genetic deletion of this gene in mice results in the delay of axon pruning and protects from axon degeneration. [provided by RefSeq, Apr 2015]

UniProt Comments for CASPASE-6

CASP6: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (p18) and a 11 kDa (p11) subunit. Interacts with BIRC6/bruce. Activation is suppressed by phosphorylation at Ser-257. Belongs to the peptidase C14A family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.22.59; Apoptosis; Protease

Cellular Component: nucleoplasm; cytoplasm; cytosol; nucleus

Molecular Function: peptidase activity; identical protein binding; protein binding; hydrolase activity; endopeptidase activity; cysteine-type peptidase activity

Biological Process: regulation of apoptosis; response to hydrogen peroxide; positive regulation of retinal cell programmed cell death; positive regulation of apoptosis; positive regulation of neuron apoptosis; response to cytokine stimulus; acute inflammatory response to non-antigenic stimulus; response to glucose stimulus; proteolysis; response to iron ion

Research Articles on CASPASE-6

1. both Caspase-3 and Caspase-6 are implicated in axon degeneration that occurs as a part of normal development.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CASPASE-6 elisa kit

Products by Pathway	Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptosis Modulation By HSP70 Pathway antibodies	Apoptosis Modulation By HSP70 Pathway Diagram
Apoptosis Signaling Pathway antibodies	Apoptosis Signaling Pathway Diagram
Apoptotic Cleavage Of Cellular Proteins Pathway antibodies	Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
Apoptotic Execution Phase Pathway antibodies	Apoptotic Execution Phase Pathway Diagram
Breakdown Of The Nuclear Lamina Pathway antibodies	Breakdown Of The Nuclear Lamina Pathway Diagram
Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway antibodies	Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway Diagram

Diseases associated with CASPASE-6 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>179 publications with CASPASE-6 and Neoplasms
Necrosis Antibodies	>77 publications with CASPASE-6 and Necrosis
Nervous System Diseases Antibodies	>72 publications with CASPASE-6 and Nervous System Diseases
Drug Toxicity Antibodies	>41 publications with CASPASE-6 and Drug Toxicity
Disease Models, Animal Antibodies	>34 publications with CASPASE-6 and Disease Models, Animal
Breast Neoplasms Antibodies	>32 publications with CASPASE-6 and Breast Neoplasms
Adenocarcinoma Antibodies	>27 publications with CASPASE-6 and Adenocarcinoma
Inflammation Antibodies	>22 publications with CASPASE-6 and Inflammation
Nerve Degeneration Antibodies	>20 publications with CASPASE-6 and Nerve Degeneration
Cognition Disorders Antibodies	>18 publications with CASPASE-6 and Cognition Disorders

Organs/Tissues associated with CASPASE-6 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>71 publications with CASPASE-6 and Brain
Liver Antibodies	>30 publications with CASPASE-6 and Liver
Lung Antibodies	>26 publications with CASPASE-6 and Lung
Skin Antibodies	>21 publications with CASPASE-6 and Skin
Muscle Antibodies	>21 publications with CASPASE-6 and Muscle
Kidney Antibodies	>21 publications with CASPASE-6 and Kidney
Prostate Antibodies	>17 publications with CASPASE-6 and Prostate
Embryonic Tissue Antibodies	>15 publications with CASPASE-6 and Embryonic Tissue
Eye Antibodies	>14 publications with CASPASE-6 and Eye
Bone Antibodies	>14 publications with CASPASE-6 and Bone