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LAG-3 Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS378176

MBS378176 is an antibody targeting LAG-3. Reactive in Mouse. Host: Rat. More details

$490 / 0.5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LAG-3, Monoclonal Antibody
Full Product Name
LAG-3
Product Gene Name
Product Synonym Names
CD223; LAG-3; Ly66
Clonality
Monoclonal
Isotype
IgG1
Clone Number
C9B7W
Host
Rat
Species Reactivity
Mouse
Purity/Purification
>95%
Concentration
2mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C.
Molecular Weight
39,103 Da
OMIM
X51985 mRNA
Preservative
None
Buffer
PBS, pH7.0
Applications Tested/Suitable for anti-LAG-3 antibody
Blocking (BL), Flow Cytometry (FC/FACS), Western Blot (WB)

Other Notes

Small volumes of anti-LAG-3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LAG-3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
LAG-3 protein, partial
NCBI Official Synonym Full Names
lymphocyte activating 3
NCBI Official Symbol
LAG3
NCBI Official Synonym Symbols
CD223
UniProt Protein Name
Lymphocyte activation gene 3 protein
UniProt Synonym Protein Names
Protein FDC; CD_antigen: CD223
UniProt Gene Name
LAG3
UniProt Synonym Gene Names
FDC; LAG-3
NCBI Protein Information
lymphocyte activation gene 3 protein

NCBI Summary for LAG-3

Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008]

UniProt Comments for LAG-3

LAG3: a cell surface receptor involved in lymphocyte activation and neural function. LAG3 expressed on neurons is a receptor that binds extracellular Alpha-synuclein fibrils (PFF) with high affinity, leading to its endocytosis. LAG3 facilitates the neuron-to-neuron spread of PFF and its associated neural toxicity. Binds to HLA class-II antigens. Two isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13.31

Cellular Component: plasma membrane

Molecular Function: antigen binding; MHC class II protein binding

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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