Neurokinin B (NKB) ELISA Kit for Porcine

Name: Porcine NKB ELISA Kit; Neurokinin B; MyBioSource
Brand: MyBioSource
SKU: MBS037835
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS037835

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used to determine the level of NKB (hereafter termed "analyte") in… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Neurokinin B (NKB), ELISA Kit

Full Product Name

Porcine Neurokinin B ELISA Kit

Product Gene Name

NKB elisa kit

Species Reactivity

Porcine

Assay Type

Quantitative Sandwich

Detection Range

15.6pg/ml-500pg/ml

Sensitivity

2.0pg/ml

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

13,438 Da

Chromosome Location

Chromosome: 12; NC_000012.11 (57403781..57410344, complement). Location: 12q13-q21

OMIM

162330

3D Structure

ModBase 3D Structure for Q9UHF0

Other Notes

Small volumes of NKB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NKB purchase

MBS037835 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Neurokinin B (NKB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NKB. The ELISA analytical biochemical technique of the MBS037835 kit is based on NKB antibody-NKB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NKB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NKB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for NKB. It may not necessarily be applicable to this product.

NCBI GI #

8572053

NCBI GeneID

6866

NCBI Accession #

AAF76980.1

UniProt Primary Accession #

Q9UHF0

UniProt Secondary Accession #

Q6IAG2; Q71BC6; Q71BC9

UniProt Related Accession #

Q9UHF0

NCBI Official Full Name

neurokinin B

NCBI Official Synonym Full Names

tachykinin 3

NCBI Official Symbol

TAC3

NCBI Official Synonym Symbols

NKB; HH10; NKNB; PRO1155; ZNEUROK1

UniProt Protein Name

Tachykinin-3

UniProt Synonym Protein Names

ZNEUROK1Cleaved into the following chain:Neurokinin-B; NKB; Alternative name(s):; Neuromedin-K

Protein Family

Neurokinin

UniProt Gene Name

TAC3

UniProt Synonym Gene Names

NKNB; NKB

UniProt Entry Name

TKNK_HUMAN

NCBI Protein Information

tachykinin-3; neuromedin K; gamma tachykinin 3; preprotachykinin B; preprotachykinin-B

NCBI Summary for NKB

This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded protein is primarily expressed in the central and peripheral nervous system and functions as a neurotransmitter. This protein is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

UniProt Comments for NKB

TAC3: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: extracellular space; extracellular region

Molecular Function: protein binding; receptor binding

Biological Process: tachykinin signaling pathway; neuropeptide signaling pathway; female pregnancy

Disease: Hypogonadotropic Hypogonadism 10 With Or Without Anosmia

Research Articles on NKB

1. Report neurokinin B immunoreactivity in the human brainstem.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NKB elisa kit

Reference Product	PubMed Publications
TACR3 elisa kit	>32 publications with NKB and TACR3
PROKR2 elisa kit	>13 publications with NKB and PROKR2
KISS1R elisa kit	>13 publications with NKB and KISS1R
GNRH1 elisa kit	>9 publications with NKB and GNRH1
TAC1 elisa kit	>8 publications with NKB and TAC1
TACR1 elisa kit	>3 publications with NKB and TACR1
TACR2 elisa kit	>2 publications with NKB and TACR2

Pathways associated with NKB elisa kit

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram
Tachykinin Receptors Bind Tachykinins Pathway antibodies	Tachykinin Receptors Bind Tachykinins Pathway Diagram

Diseases associated with NKB elisa kit

Disease Name	Pubmed Publications
Hypogonadism Antibodies	>28 publications with NKB and Hypogonadism
Congenital Abnormalities Antibodies	>9 publications with NKB and Congenital Abnormalities
Olfaction Disorders Antibodies	>3 publications with NKB and Olfaction Disorders
Mental Disorders Antibodies	>1 publications with NKB and Mental Disorders
Hypersensitivity Antibodies	>1 publications with NKB and Hypersensitivity
Neurobehavioral Manifestations Antibodies	>1 publications with NKB and Neurobehavioral Manifestations

Organs/Tissues associated with NKB elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>10 publications with NKB and Brain
Placenta Antibodies	>2 publications with NKB and Placenta
Uterus Antibodies	>1 publications with NKB and Uterus
Connective Tissue Antibodies	>1 publications with NKB and Connective Tissue
Embryonic Tissue Antibodies	>1 publications with NKB and Embryonic Tissue