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Cytochrome P450 3a43 (CYP3A43) Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS003828

MBS003828 is an antibody targeting CYP3A43. Also known as Rabbit Cytochrome P450 3A43 Antibody. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
Cytochrome P450 3A43 (CYP3A43), Antibody
Full Product Name
Rabbit Cytochrome P450 3A43 Antibody
Product Gene Name
Host
Rabbit
Species Reactivity
Human
Form/Format
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (lot specific)
Molecular Weight
57,670 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (99425636..99464173). Location: 7q21.1
OMIM
606534
3D Structure
ModBase 3D Structure for Q9HB55
Applications Tested/Suitable for anti-CYP3A43 antibody
ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-CYP3A43 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CYP3A43. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cytochrome P450 3A43 isoform 1
NCBI Official Synonym Full Names
cytochrome P450, family 3, subfamily A, polypeptide 43
NCBI Official Symbol
CYP3A43
UniProt Protein Name
Cytochrome P450 3A43
Protein Family
UniProt Gene Name
CYP3A43
UniProt Entry Name
CP343_HUMAN
NCBI Protein Information
cytochrome P450 3A43; cytochrome P450 polypeptide 43; cytochrome P450, subfamily IIIA, polypeptide 43

NCBI Summary for CYP3A43

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, it is unknown whether the enzyme is also involved in xenobiotic metabolism. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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UniProt Comments for CYP3A43

CYP3A43: Exhibits low testosterone 6-beta-hydroxylase activity. Belongs to the cytochrome P450 family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.14.14.1; Oxidoreductase; Lipid Metabolism - linoleic acid; Xenobiotic Metabolism - metabolism by cytochrome P450; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - drug metabolism - other enzymes

Chromosomal Location of Human Ortholog: 7q21.1

Cellular Component: endoplasmic reticulum membrane

Molecular Function: iron ion binding; heme binding; monooxygenase activity

Biological Process: xenobiotic metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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