Rabbit Anti-CCDC99 Antibody – Cat# MBS003900

CCDC99 Antibody – Rabbit

Name: CCDC99 Antibody; Rabbit; Human-Reactive; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS003900
Price: 595 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS003900

MBS003900 is an antibody targeting CCDC99. Also known as Rabbit CCDC99 Antibody. Reactive in Human. Host: Rabbit. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CCDC99, Antibody

Full Product Name

Rabbit CCDC99 Antibody

Product Gene Name

anti-CCDC99 antibody

Host

Rabbit

Species Reactivity

Human

Form/Format

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Concentration

1 mg/ml (lot specific)

Molecular Weight

70,172 Da

Chromosome Location

Chromosome: 5; NC_000005.9 (169010638..169031782). Location: 5q35.1

3D Structure

ModBase 3D Structure for Q96EA4

Applications Tested/Suitable for anti-CCDC99 antibody

ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-CCDC99 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CCDC99. It may not necessarily be applicable to this product.

NCBI GI #

157388975

NCBI GeneID

54908

NCBI Accession #

NP_060255.3

UniProt Primary Accession #

Q96EA4

UniProt Secondary Accession #

Q8TEC8; Q9HD44; Q9NX97; C9JS47

UniProt Related Accession #

Q96EA4

GenBank Nucleotide #

NM_017785.4

NCBI Official Full Name

protein Spindly

NCBI Official Synonym Full Names

spindle apparatus coiled-coil protein 1

NCBI Official Symbol

SPDL1

NCBI Official Synonym Symbols

CCDC99

UniProt Protein Name

Protein Spindly

UniProt Synonym Protein Names

Arsenite-related gene 1 protein; Coiled-coil domain-containing protein 99; Rhabdomyosarcoma antigen MU-RMS-40.4A; Spindle apparatus coiled-coil domain-containing protein 1

UniProt Gene Name

SPDL1

UniProt Synonym Gene Names

CCDC99; hSpindly

UniProt Entry Name

SPDLY_HUMAN

NCBI Protein Information

protein Spindly; hSpindly; spindly homolog; arsenite-related gene 1 protein; coiled-coil domain containing 99; rhabdomyosarcoma antigen MU-RMS-40.4A; coiled-coil domain-containing protein 99; rrhabdomyosarcoma antigen protein MU-RMS-40.4A; spindle apparatus coiled-coil domain-containing protein 1

UniProt Comments for CCDC99

CCDC99: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Belongs to the Spindly family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 5q35.1

Cellular Component: spindle pole; microtubule organizing center; outer kinetochore of condensed chromosome; cytosol; nucleus

Molecular Function: kinetochore binding; protein binding; enzyme binding

Biological Process: establishment of mitotic spindle orientation; spindle checkpoint; cell division; mitotic cell cycle; mitotic metaphase plate congression

Research Articles on CCDC99

1. Spindly is not only required for kinetochore localization of dynein but is a functional component of a mechanism that couples dynein-dependent poleward movement of chromosomes to their efficient attachment to microtubules.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CCDC99 antibody

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