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TAFII68 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3900922

The TFIID complex is important for coordinating the pre-initiation complex and transcription by RNA Pol II. The complex contains the TFIID protein, TATA binding protein (TBP) and multiple TBP-associated factors (TAFs). TAFII68 was identified as a subunit of… More details

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Product Overview

Online Datasheet in PDF
Product Name
TAFII68, Polyclonal Antibody
Full Product Name
Rabbit anti-TAFII68 Antibody, Affinity Purified
Product Gene Name
anti-TAFII68 antibody
Product Synonym Gene Name
TAF15
Product Synonym Names
TAF2N; TBP-associated factor 15; TATA-binding protein-associated factor 2N; TATA box-binding protein-associated factor 2N (RNA-binding protein 56); TAFII68; TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa; 68 kDa TATA-binding protein-associated factor; RNA-binding protein 56; RBP56/CSMF fusion; RBP56; Npl3; TAF(II)68; TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56); TATA-binding protein-associated factor 2N; TATA-box binding protein associated factor 15
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
61,830 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (34136459..34174246). Location: 17q11.1-q11.2
OMIM
601574
3D Structure
ModBase 3D Structure for Q92804
Immunogen
Between 200 and 250
Conjugation
Unconjugated

Product Categories/Family for anti-TAFII68 antibody

Primary Antibodies
Applications Tested/Suitable for anti-TAFII68 antibody
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
Application Notes for anti-TAFII68 antibody
WB: 1:5000-1:20,000
IP: 6ug/mg lysate
IHC: 1:1000-1:5000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Immunohistochemistry (IHC) of anti-TAFII68 antibody

Detection of human TAFII68 by immunohistochemistry. Sample: FFPE section of human testicular seminoma. Antibody: Affinity purified rabbit anti-TAFII68 (Cat. No. MBS3900922 Lot1) used at a dilution of 1:5,000 (0.2ug/ml). Detection: DAB
Rabbit Anti-TAFII68 Polyclonal Antibody – Cat# MBS3900922

Western Blot (WB) of anti-TAFII68 antibody

Detection of human TAFII68 by western blot and immunoprecipitation. Samples: Whole cell lysate (200 ug for WB; 10 mg for IP/WB) from HEK293T cells. Antibodies: Affinity purified rabbit anti-TAFII68 antibody BL1357 (Cat. No. MBS3900922) used at 0.1 ug/ml for WB. TAFII68 was immunoprecipitated with rabbit anti-TAFII68 antibodies BL1356 (Cat. No. MBS3900921), BL1357, BL1358 and BL1359 (Cat. No. MBS3900923) using each at 0.3 ug/mg lysate. Detection: Chemiluminescence with an exposure time of 5 seconds.
Rabbit Anti-TAFII68 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3900922

Other Notes

Small volumes of anti-TAFII68 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TAFII68 purchase

MBS3900922 is an antibody targeting TAFII68. Also known as Rabbit anti-TAFII68 Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TAFII68. It may not necessarily be applicable to this product.

NCBI GI #
21327701
NCBI GeneID
8148
NCBI Accession #
NP_631961.1
UniProt Primary Accession #
Q92804
UniProt Secondary Accession #
Q92751; B2R837
UniProt Related Accession #
Q92804
GenBank Nucleotide #
NM_139215.2
NCBI Official Full Name
TATA-binding protein-associated factor 2N isoform 1
NCBI Official Synonym Full Names
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
NCBI Official Symbol
TAF15
NCBI Official Synonym Symbols
Npl3; RBP56; TAF2N; TAFII68
UniProt Protein Name
TATA-binding protein-associated factor 2N
UniProt Synonym Protein Names
68 kDa TATA-binding protein-associated factor; TAF(II)68; TAFII68; RNA-binding protein 56
Protein Family
TATA-binding protein-associated factor
UniProt Gene Name
TAF15
UniProt Synonym Gene Names
RBP56; TAF2N; TAF(II)68; TAFII68
UniProt Entry Name
RBP56_HUMAN
NCBI Protein Information
TATA-binding protein-associated factor 2N; RBP56/CSMF fusion; TBP-associated factor 15; TATA box-binding protein-associated factor 2N (RNA-binding protein 56); TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding prote

UniProt Comments for TAFII68

TAF15: RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II). A chromosomal aberration involving TAF15/TAF2N is found in a form of extraskeletal myxoid chondrosarcomas (EMC). Translocation t(9;17)(q22;q11) with NR4A3. Belongs to the RRM TET family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Translation; Oncoprotein; RNA-binding

Chromosomal Location of Human Ortholog: 17q11.1-q11.2

Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus

Molecular Function: protein binding; DNA binding; zinc ion binding; nucleotide binding

Biological Process: positive regulation of transcription, DNA-dependent

Disease: Chondrosarcoma, Extraskeletal Myxoid
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TAFII68 antibody

 Reference Product  PubMed Publications
 NR4A3 antibody  >12 publications with TAFII68 and NR4A3
 TBP antibody  >7 publications with TAFII68 and TBP
 ZNF384 antibody  >6 publications with TAFII68 and ZNF384
 TCF12 antibody  >3 publications with TAFII68 and TCF12
 PRMT1 antibody  >1 publications with TAFII68 and PRMT1

Pathways associated with anti-TAFII68 antibody

 Products by Pathway  Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram

Diseases associated with anti-TAFII68 antibody

 Disease Name  Pubmed Publications
 Osteosarcoma Antibodies  >5 publications with TAFII68 and Osteosarcoma
 Chondrosarcoma, Extraskeletal Myxoid Antibodies  >4 publications with TAFII68 and Chondrosarcoma, Extraskeletal Myxoid
 Immune System Diseases Antibodies  >3 publications with TAFII68 and Immune System Diseases
 Lung Neoplasms Antibodies  >2 publications with TAFII68 and Lung Neoplasms
 Cell Transformation, Neoplastic Antibodies  >2 publications with TAFII68 and Cell Transformation, Neoplastic
 Disease Models, Animal Antibodies  >1 publications with TAFII68 and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >1 publications with TAFII68 and Neoplasms, Experimental
 Carcinoma Antibodies  >1 publications with TAFII68 and Carcinoma
 Disease Progression Antibodies  >1 publications with TAFII68 and Disease Progression
 Fibrosis Antibodies  >1 publications with TAFII68 and Fibrosis

Organs/Tissues associated with anti-TAFII68 antibody

 Organ/Tissue Name  Pubmed Publications
 Thyroid Antibodies  >9 publications with TAFII68 and Thyroid
 Brain Antibodies  >9 publications with TAFII68 and Brain
 Connective Tissue Antibodies  >4 publications with TAFII68 and Connective Tissue
 Muscle Antibodies  >3 publications with TAFII68 and Muscle
 Vascular Antibodies  >2 publications with TAFII68 and Vascular
 Lung Antibodies  >2 publications with TAFII68 and Lung
 Blood Antibodies  >1 publications with TAFII68 and Blood
 Eye Antibodies  >1 publications with TAFII68 and Eye
 Embryonic Tissue Antibodies  >1 publications with TAFII68 and Embryonic Tissue
 Stomach Antibodies  >1 publications with TAFII68 and Stomach
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