Rabbit Anti-TRIP6 Polyclonal Antibody – Cat# MBS3900937

Detection of human TRIP6 by western blot. Samples: Whole cell lysate (50 ug) from HeLa and HEK293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-TRIP6 antibody MBS3900937 (lot MBS3900937-2) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

TRIP6 Antibody – Rabbit Polyclonal

Name: TRIP6 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS3900937
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3900937

Thyroid receptor interacting protein 6 (TRIP6) was identified as a protein that interacts with the thyroid receptor. TRIP6 is a LIM domain-containing protein and is in the same family as the adhesion plaque protein, zyxin and lipoma preferred partner (LPP).… More details

$250 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TRIP6, Polyclonal Antibody

Full Product Name

Rabbit anti-TRIP6 Antibody, Affinity Purified

Product Gene Name

anti-TRIP6 antibody

Product Synonym Names

TRIP-6; OIP1; Zyxin-related protein 1; zyxin related protein 1; ZRP-1; TRIP6i2; thyroid receptor-interacting protein 6; thyroid hormone receptor interacting protein 6; OIP-1; OPA-interacting protein 1; TR-interacting protein 6; Thyroid receptor-interacting protein 6; thyroid hormone receptor interactor 6

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Purity/Purification

Antigen Affinity Purified

Concentration

1000ug/ml (lot specific)

Preparation and Storage

Store at 2-8 degree C
Shelf Life: 1 year from date of receipt

Molecular Weight

8,277 Da

OMIM

602933

3D Structure

ModBase 3D Structure for Q15654

Immunogen

Between 100 and 150

Conjugation

Unconjugated

Product Categories/Family for anti-TRIP6 antibody

Primary Antibodies

Applications Tested/Suitable for anti-TRIP6 antibody

Western Blot (WB)

Application Notes for anti-TRIP6 antibody

WB: 1:1000-1:10,000

Other Notes

Small volumes of anti-TRIP6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRIP6 purchase

MBS3900937 is an antibody targeting TRIP6. Also known as Rabbit anti-TRIP6 Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TRIP6. It may not necessarily be applicable to this product.

NCBI GI #

91208423

NCBI GeneID

7205

NCBI Accession #

NP_003293.2

UniProt Primary Accession #

Q15654

UniProt Secondary Accession #

O15170; O15275; Q9BTB2; Q9BUE5; Q9BXP3; Q9UNT4; A4D2E7; F2ZC07; F2ZC08

UniProt Related Accession #

Q15654

GenBank Nucleotide #

NM_003302.2

NCBI Official Full Name

thyroid receptor-interacting protein 6

NCBI Official Synonym Full Names

thyroid hormone receptor interactor 6

NCBI Official Symbol

TRIP6

NCBI Official Synonym Symbols

OIP1; OIP-1; ZRP-1; TRIP-6; TRIP6i2

UniProt Protein Name

Thyroid receptor-interacting protein 6

UniProt Synonym Protein Names

Opa-interacting protein 1; OIP-1; Zyxin-related protein 1; ZRP-1

Protein Family

Thyroid receptor-interacting protein

UniProt Gene Name

TRIP6

UniProt Synonym Gene Names

OIP1; TR-interacting protein 6; TRIP-6; OIP-1; ZRP-1

UniProt Entry Name

TRIP6_HUMAN

NCBI Protein Information

thyroid receptor-interacting protein 6

NCBI Summary for TRIP6

This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

UniProt Comments for TRIP6

TRIP6: thyroid receptor interacting protein 6 specifically interacts with the ligand-binding domain of the thyroid receptor (TR). Requires the presence of thyroid hormone for its interaction. Interacts with PTPN13. Functions downstream of the activated LPA(2) receptor and is involved in cell adhesion and migration.

Protein type: Nuclear receptor co-regulator; Motility/polarity/chemotaxis; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 7q22

Cellular Component: interleukin-1 receptor complex; cytoskeleton; focal adhesion; cytoplasm; plasma membrane; nucleus

Molecular Function: protein binding; interleukin-1 receptor binding; zinc ion binding; thyroid hormone receptor binding; kinase binding

Biological Process: release of cytoplasmic sequestered NF-kappaB; focal adhesion formation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of cell migration

Research Articles on TRIP6

1. the Trip6-GRIP1-myosin VI interaction and its regulation on F-actin network play a significant role in dendritic morphogenesis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TRIP6 antibody

Reference Product	PubMed Publications
SRC antibody	>8 publications with TRIP6 and SRC
CRK antibody	>4 publications with TRIP6 and CRK
PTPN13 antibody	>3 publications with TRIP6 and PTPN13
JUN antibody	>2 publications with TRIP6 and JUN
FOS antibody	>2 publications with TRIP6 and FOS
RIPK2 antibody	>1 publications with TRIP6 and RIPK2
PTK2 antibody	>1 publications with TRIP6 and PTK2

Pathways associated with anti-TRIP6 antibody

Products by Pathway	Pathway Diagram
LPA Receptor Mediated Events Pathway antibodies	LPA Receptor Mediated Events Pathway Diagram
NOD-like Receptor Signaling Pathway antibodies	NOD-like Receptor Signaling Pathway Diagram
NOD-like Receptor Signaling Pathway antibodies	NOD-like Receptor Signaling Pathway Diagram

Diseases associated with anti-TRIP6 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>2 publications with TRIP6 and Inflammation
Necrosis Antibodies	>2 publications with TRIP6 and Necrosis
Breast Neoplasms Antibodies	>1 publications with TRIP6 and Breast Neoplasms
Nervous System Diseases Antibodies	>1 publications with TRIP6 and Nervous System Diseases
Cell Transformation, Neoplastic Antibodies	>1 publications with TRIP6 and Cell Transformation, Neoplastic

Organs/Tissues associated with anti-TRIP6 antibody

Organ/Tissue Name	Pubmed Publications
Thyroid Antibodies	>37 publications with TRIP6 and Thyroid
Muscle Antibodies	>3 publications with TRIP6 and Muscle
Bone Antibodies	>2 publications with TRIP6 and Bone
Intestine Antibodies	>2 publications with TRIP6 and Intestine
Blood Antibodies	>1 publications with TRIP6 and Blood
Pancreas Antibodies	>1 publications with TRIP6 and Pancreas
Skin Antibodies	>1 publications with TRIP6 and Skin
Embryonic Tissue Antibodies	>1 publications with TRIP6 and Embryonic Tissue
Spleen Antibodies	>1 publications with TRIP6 and Spleen
Lung Antibodies	>1 publications with TRIP6 and Lung