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Apolipoprotein CII (APO CII) Antibody – Goat

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS390099

MBS390099 is an antibody targeting Apo CII. Also known as Goat Anti-Recombinant-Human Apolipoprotein CII Neat Antiseum. Host: Goat. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Apolipoprotein CII (Apo CII), Antibody
Full Product Name
Goat Anti-Recombinant-Human Apolipoprotein CII Neat Antiseum
Product Gene Name
Product Synonym Names
Goat Anti-Recombinant-Human Apolipoprotein CII (ApoCII), Polyclonal Antibody; Neat Antiserum
Host
Goat
Specificity
Specifically binds to human apo CII. Dilution for immunoblot and ELISA range: 200 to 80,000.
Preparation and Storage
-20 degree C for long-term storage, 2-8 degree C for short-term storage. Aliquot to avoid repeated freezing and thawing.
Molecular Weight
11,284 Da
Chromosome Location
Chromosome: 19; NC_000019.9 (45449239..45452822). Location: 19q13.2
OMIM
207750
3D Structure
ModBase 3D Structure for P02655
Source Note
Produced by injection of recombinant human apo CII and boosted with pure human apo CII.*
Preservative
With 0.1% NaN3.

Product Categories/Family for anti-Apo CII antibody

Applications Tested/Suitable for anti-Apo CII antibody
ELISA (EIA), Immunoblot (IB)
Application Notes for anti-Apo CII antibody
Dilution for Immunoblot & ELISA range: 1,000 to 80,000.
Use: The antibody can be used for detection of human apo CII in plasma and lipoproteins, Immunoassays, and immunoblots.

Other Notes

Small volumes of anti-Apo CII antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Apo CII. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
apolipoprotein CII
NCBI Official Synonym Full Names
apolipoprotein C-II
NCBI Official Symbol
APOC2
NCBI Official Synonym Symbols
APO-CII; APOC-II
UniProt Protein Name
Apolipoprotein C-II
UniProt Synonym Protein Names
Apolipoprotein C2
UniProt Gene Name
APOC2
UniProt Synonym Gene Names
APC2; Apo-CII; ApoC-II
UniProt Entry Name
APOC2_HUMAN
NCBI Protein Information
apolipoprotein C-II; apolipoprotein C2

NCBI Summary for Apo CII

This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene. [provided by RefSeq, Mar 2011]
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UniProt Comments for Apo CII

Function: Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly.

Subcellular location: Secreted.

Tissue specificity: Secreted in plasma.

Involvement in disease: Hyperlipoproteinemia 1B (HLPP1B) [MIM:207750]: Autosomal recessive trait characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.23

Sequence similarities: Belongs to the apolipoprotein C2 family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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