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MAVS/VISA Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3901298

Mitochondrial Antiviral-Signaling Protein (MAVS), also known as Virus-Induced Signaling Adaptor (VISA), is an adaptor protein that functions in the activation of the nuclear factor KappaB (NF-kappaB) and interferon regulatory factor 3 (IRF3) to mediate host… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
MAVS/VISA, Polyclonal Antibody
Full Product Name
Rabbit anti-MAVS/VISA Antibody, Affinity Purified
Product Gene Name
Product Synonym Gene Name
MAVS
Product Synonym Names
IPS1; virus-induced-signaling adapter; virus-induced signaling adaptor; putative NF-kappa-B-activating protein 031N; mitochondrial antiviral-signaling protein; VISA; interferon beta promoter stimulator protein 1; IFN-B promoter stimulator 1; CARDIF; CARD adaptor inducing IFN-beta; CARD adapter inducing interferon beta; MAVS; IPS-1; Mitochondrial antiviral-signaling protein; mitochondrial antiviral signaling protein
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
15,012 Da
OMIM
609676
3D Structure
ModBase 3D Structure for Q7Z434
Immunogen
Between 275 and 325
Conjugation
Unconjugated

Product Categories/Family for anti-MAVS/VISA antibody

Applications Tested/Suitable for anti-MAVS/VISA antibody
Immunoprecipitation (IP)
Application Notes for anti-MAVS/VISA antibody
IP: 6ug/mg lysate

Immunoprecipitation (IP) of anti-MAVS/VISA antibody

Detection of human MAVS/VISA by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-MAVS(VISA) antibody BL3173 (Cat. No. MBS3901298) used for IP at 3 ug/mg lysate. MAVS(VISA) was also immunoprecipitated by rabbit anti-MAVS/VISA antibody BL3172 (Cat. No. MBS3901297). For blotting immunoprecipitated MAVS/VISA, BL3172 was used at 1 ug/mg lysate. Detection: Chemiluminescence with an exposure time of 30 seconds.
Rabbit Anti-MAVS/VISA Polyclonal Antibody – Cat# MBS3901298

Other Notes

Small volumes of anti-MAVS/VISA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MAVS/VISA purchase

MBS3901298 is an antibody targeting MAVS/VISA. Also known as Rabbit anti-MAVS/VISA Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MAVS/VISA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Virus-induced signaling adapter
NCBI Official Synonym Full Names
mitochondrial antiviral signaling protein
NCBI Official Symbol
MAVS
NCBI Official Synonym Symbols
IPS1; VISA; IPS-1; CARDIF
UniProt Protein Name
Mitochondrial antiviral-signaling protein
UniProt Synonym Protein Names
CARD adapter inducing interferon beta; Cardif; Interferon beta promoter stimulator protein 1; IPS-1; Putative NF-kappa-B-activating protein 031N; Virus-induced-signaling adapter
UniProt Gene Name
MAVS
UniProt Synonym Gene Names
IPS1; KIAA1271; VISA; MAVS; Cardif; IPS-1; VISA
UniProt Entry Name
MAVS_HUMAN
NCBI Protein Information
mitochondrial antiviral-signaling protein

NCBI Summary for MAVS/VISA

This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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