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GTF3C3/TFIIIC102 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3901743

General transcription factor 3C polypeptide 3 (GTF3C3/TFIIIC102) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110,… More details

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Product Overview

Online Datasheet in PDF
Product Name
GTF3C3/TFIIIC102, Polyclonal Antibody
Full Product Name
Rabbit anti-GTF3C3/TFIIIC102 Antibody, Affinity Purified
Product Synonym Gene Name
GTF3C3
Product Synonym Names
TFIIIC 102 kDa subunit; transcription factor IIIC subunit gamma; Transcription factor IIIC 102 kDa subunit; TFIIICgamma; TFIIIC102; TF3C-gamma; general transcription factor IIIC, polypeptide 3, 102kDa; general transcription factor 3C polypeptide 3; TFiiiC2-102; General transcription factor 3C polypeptide 3; general transcription factor IIIC subunit 3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
47,258 Da
OMIM
604888
3D Structure
ModBase 3D Structure for Q9Y5Q9
Immunogen
Between 125 and 175
Conjugation
Unconjugated
Applications Tested/Suitable for anti-GTF3C3/TFIIIC102 antibody
Immunoprecipitation (IP)
Application Notes for anti-GTF3C3/TFIIIC102 antibody
IP: 6ug/mg lysate

Immunoprecipitation (IP) of anti-GTF3C3/TFIIIC102 antibody

Detection of human GTF3C3/TFIIIC102 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-GTF3C3/TFIIIC102 antibody MBS3901743 used for IP at 3 ug/mg lysate. GTF3C3/TFIIIC102 was also immunoprecipitated by rabbit anti-GTF3C3/TFIIIC102 antibody MBS3901744, which recognizes a downstream epitope. For blotting immunoprecipitated GTF3C3/TFIIIC102, MBS3901744 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Rabbit Anti-GTF3C3/TFIIIC102 Polyclonal Antibody – Cat# MBS3901743

Other Notes

Small volumes of anti-GTF3C3/TFIIIC102 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GTF3C3/TFIIIC102 purchase

MBS3901743 is an antibody targeting GTF3C3/TFIIIC102. Also known as Rabbit anti-GTF3C3/TFIIIC102 Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GTF3C3/TFIIIC102. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
general transcription factor 3C polypeptide 3 isoform 1
NCBI Official Synonym Full Names
general transcription factor IIIC, polypeptide 3, 102kDa
NCBI Official Symbol
GTF3C3
NCBI Official Synonym Symbols
TFIIIC102; TFIIICgamma; TFiiiC2-102
UniProt Protein Name
General transcription factor 3C polypeptide 3
UniProt Synonym Protein Names
Transcription factor IIIC 102 kDa subunit; TFIIIC 102 kDa subunit; TFIIIC102; Transcription factor IIIC subunit gamma
UniProt Gene Name
GTF3C3
UniProt Synonym Gene Names
TFIIIC 102 kDa subunit; TFIIIC102; TF3C-gamma
UniProt Entry Name
TF3C3_HUMAN
NCBI Protein Information
general transcription factor 3C polypeptide 3; TF3C-gamma; TFIIIC 102 kDa subunit; transcription factor IIIC subunit gamma

NCBI Summary for GTF3C3/TFIIIC102

The protein encoded by this gene is part of the TFIIIC2 complex, which binds to the promoters of small nuclear and cytoplasmic RNA genes in order to recruit RNA polymerase III. The TFIIIC2 complex is composed of six subunits. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
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UniProt Comments for GTF3C3/TFIIIC102

GTF3C3: Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 2q33.1

Cellular Component: nucleoplasm; transcription factor TFIIIC complex

Molecular Function: protein binding; DNA binding

Biological Process: transcription from RNA polymerase III promoter; transcription, DNA-dependent; 5S class rRNA transcription; gene expression; tRNA transcription from RNA polymerase III promoter
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Research Articles on GTF3C3/TFIIIC102

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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