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IKK-alpha Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3902363

I kappa-B kinase-alpha (IKK-alpha) is part of the IKK complex composed of two regulatory subunits, IKK-alpha and IKK-beta, and a regulatory subunit, IKK-gamma/NEMO. The IKK complex functions to phosphorylate and inactivate I kappa B, an inhibitor of the… More details

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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
IKK-alpha, Polyclonal Antibody
Full Product Name
Rabbit anti-IKK-alpha Antibody, Affinity Purified
Product Gene Name
Product Synonym Gene Name
CHUK
Product Synonym Names
IKK-alpha; transcription factor 16; TCF-16; TCF16; Nuclear factor NF-kappa-B inhibitor kinase alpha; Nuclear factor NFkappaB inhibitor kinase alpha; inhibitor of nuclear factor kappa-B kinase subunit alpha; IKK-a kinase; IKK-A; IkappaB kinase; IKK1; Conserved helix-loop-helix ubiquitous kinase; IKBKA; IkB kinase alpha subunit; I-kappa-B kinase-alpha; I-kappa-B kinase alpha; I-kappa-B kinase 1; IKKA; NFKBIKA; Inhibitor of nuclear factor kappa-B kinase subunit alpha; conserved helix-loop-helix ubiquitous kinase
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
84,640 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (101948124..101989344, complement). Location: 10q24-q25
OMIM
600664
3D Structure
ModBase 3D Structure for O15111
Predicted Reactivity
Bovine
Immunogen
Between 550 and 600
Conjugation
Unconjugated

Product Categories/Family for anti-IKK-alpha antibody

Applications Tested/Suitable for anti-IKK-alpha antibody
Immunoprecipitation (IP)
Application Notes for anti-IKK-alpha antibody
IP: 6ug/mg lysate

Immunoprecipitation (IP) of anti-IKK-alpha antibody

Detection of human IKK-alpha by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from Jurkat cells. Antibodies: Affinity purified rabbit anti-IKK-alpha antibody MBS3902363 used for IP at 3 ug/mg lysate. IKK-alpha was also immunoprecipitated by rabbit anti-IKK-alpha antibody A301-933A, which recognizes an upstream epitope. For blotting immunoprecipitated IKK-alpha, A301-933A was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Rabbit Anti-IKK-alpha Polyclonal Antibody – Cat# MBS3902363

Other Notes

Small volumes of anti-IKK-alpha antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IKK-alpha purchase

MBS3902363 is an antibody targeting IKK-alpha. Also known as Rabbit anti-IKK-alpha Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IKK-alpha. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
inhibitor of nuclear factor kappa-B kinase subunit alpha
NCBI Official Synonym Full Names
conserved helix-loop-helix ubiquitous kinase
NCBI Official Symbol
CHUK
NCBI Official Synonym Symbols
IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha
UniProt Protein Name
Inhibitor of nuclear factor kappa-B kinase subunit alpha
UniProt Synonym Protein Names
Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B inhibitor kinase alpha; NFKBIKA; Transcription factor 16
UniProt Gene Name
CHUK
UniProt Synonym Gene Names
IKKA; TCF16; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; IKK1; NFKBIKA; TCF-16
UniProt Entry Name
IKKA_HUMAN
NCBI Protein Information
inhibitor of nuclear factor kappa-B kinase subunit alpha; TCF-16; IKK-a kinase; I-kappa-B kinase 1; I-kappa-B kinase-alpha; transcription factor 16; IkB kinase alpha subunit; Nuclear factor NFkappaB inhibitor kinase alpha

NCBI Summary for IKK-alpha

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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