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MLLT1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3902673

MLLT1, also known as ENL (eleven nineteen leukemia protein), was originally identified as a gene involved in a recurrent translocation (11;19) with the mixed-lineage leukemia (MLL) gene. The MLL-ENL fusion protein has been found to associate with SWI/SNF… More details

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Product Overview

Online Datasheet in PDF
Product Name
MLLT1, Polyclonal Antibody
Full Product Name
Rabbit anti-MLLT1 Antibody, Affinity Purified
Product Gene Name
Product Synonym Names
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1; YEATS1; protein ENL; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 1; MLL/ENL fusion protein; LTG19; ENL/MLL fusion; ENL; CTC-503J8.6; MLLT1/MLL fusion; YEATS domain-containing protein 1; Protein ENL; MLLT1, super elongation complex subunit
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
62,056 Da
OMIM
159556
3D Structure
ModBase 3D Structure for Q03111
Immunogen
Between 150 and 200
Conjugation
Unconjugated

Product Categories/Family for anti-MLLT1 antibody

Applications Tested/Suitable for anti-MLLT1 antibody
Immunoprecipitation (IP)
Application Notes for anti-MLLT1 antibody
IP: 6ug/mg lysate

Immunoprecipitation (IP) of anti-MLLT1 antibody

Detection of human MLLT1 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-MLLT1 antibody MBS3902673 used for IP at 3 ug/mg lysate. MLLT1 was also immunoprecipitated by rabbit anti-MLLT1 antibody MBS3902674, which recognizes a downstream epitope. For blotting immunoprecipitated MLLT1, MBS3902674 was used at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Rabbit Anti-MLLT1 Polyclonal Antibody – Cat# MBS3902673

Other Notes

Small volumes of anti-MLLT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MLLT1 purchase

MBS3902673 is an antibody targeting MLLT1. Also known as Rabbit anti-MLLT1 Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MLLT1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein ENL
NCBI Official Synonym Full Names
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
NCBI Official Symbol
MLLT1
NCBI Official Synonym Symbols
ENL; LTG19; YEATS1
UniProt Protein Name
Protein ENL
UniProt Synonym Protein Names
YEATS domain-containing protein 1
Protein Family
UniProt Gene Name
MLLT1
UniProt Synonym Gene Names
ENL; LTG19; YEATS1
UniProt Entry Name
ENL_HUMAN
NCBI Protein Information
protein ENL; CTC-503J8.6; ENL/MLL fusion; MLLT1/MLL fusion; YEATS domain-containing protein 1; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 1

UniProt Comments for MLLT1

MLLT1: a transcriptional regulator that can activate transcription from synthetic reporter genes in both lymphoid and myeloid cells. A chromosomal aberration involving MLLT1 is associated with acute leukemias.

Protein type: Oncoprotein; Transcription regulation

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: nucleoplasm; transcription elongation factor complex; cytoplasm; nucleolus; nucleus

Molecular Function: protein binding; DNA binding

Biological Process: transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; negative regulation of protein kinase activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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