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SAP130 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3902870

Sin3-associated polypeptide p130 (SAP130) is a component of an mSin3A corepressor complex. SAP130 acts as a transcriptional repressor. It may function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions… More details

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Product Overview

Online Datasheet in PDF
Product Name
SAP130, Polyclonal Antibody
Full Product Name
Rabbit anti-SAP130 Antibody, Affinity Purified
Product Gene Name
Product Synonym Names
Sin3-associated polypeptide p130; Sin3A associated protein 130kDa; 130 kDa Sin3-associated polypeptide; histone deacetylase complex subunit SAP130; Histone deacetylase complex subunit SAP130; Sin3A associated protein 130
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
OMIM
609697
3D Structure
ModBase 3D Structure for Q9H0E3
Predicted Reactivity
Mouse, Chicken
Immunogen
Between 998 and C-terminus
Conjugation
Unconjugated

Product Categories/Family for anti-SAP130 antibody

Applications Tested/Suitable for anti-SAP130 antibody
Immunoprecipitation (IP)
Application Notes for anti-SAP130 antibody
IP: 6ug/mg lysate

Immunoprecipitation (IP) of anti-SAP130 antibody

Detection of human SAP130 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-SAP130 antibody MBS3902870 used for IP at 3 ug/mg lysate. SAP130 was also immunoprecipitated by rabbit anti-SAP130 antibody MBS3902869, which recognizes an upstream epitope. For blotting immunoprecipitated SAP130, MBS3902869 was used at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
Rabbit Anti-SAP130 Polyclonal Antibody – Cat# MBS3902870

Other Notes

Small volumes of anti-SAP130 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SAP130 purchase

MBS3902870 is an antibody targeting SAP130. Also known as Rabbit anti-SAP130 Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SAP130. It may not necessarily be applicable to this product.

NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Protein Name
Histone deacetylase complex subunit SAP130
UniProt Synonym Protein Names
130 kDa Sin3-associated polypeptide; Sin3-associated polypeptide p130
UniProt Gene Name
SAP130
UniProt Entry Name
SP130_HUMAN

UniProt Comments for SAP130

SAP130: Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. Belongs to the SAP130 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; Acetyltransferase

Chromosomal Location of Human Ortholog: 2q14.3

Cellular Component: nucleoplasm

Molecular Function: histone acetyltransferase activity; transcription coactivator activity

Biological Process: establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; negative regulation of gene expression, epigenetic; gene expression; negative regulation of transcription from RNA polymerase II promoter; regulation of gene expression, epigenetic
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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