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CHD1L Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3903623

Chromodomain-helicase-DNA-binding protein 1-like (CHD1L) is a DNA helicase which plays a role in chromatin-remodeling following DNA damage. CHD1L is targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CHD1L, Polyclonal Antibody
Full Product Name
Rabbit anti-CHD1L Antibody, Affinity Purified
Product Gene Name
Product Synonym Names
ALC1; amplified in liver cancer 1; amplified in liver cancer protein 1; CHDL; chromodomain-helicase-DNA-binding protein 1-like; Chromodomain-helicase-DNA-binding protein 1-like; chromodomain helicase DNA binding protein 1 like
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
200ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
100,984 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (146714291..146767443). Location: 1q12
OMIM
613039
3D Structure
ModBase 3D Structure for Q86WJ1
Immunogen
Between 575 and 625
Conjugation
Unconjugated

Product Categories/Family for anti-CHD1L antibody

Applications Tested/Suitable for anti-CHD1L antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-CHD1L antibody
WB: 1:2000-1:10,000
IP: 6ug/mg lysate

Western Blot (WB) of anti-CHD1L antibody

Detection of human CHD1L by western blot and immunoprecipitation. Samples: Whole cell lysate from HEK293T (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and Jurkat (J; 50 ug) cells. Antibodies: Affinity purified rabbit anti-CHD1L antibody MBS3903623 used for WB at 0.04 ug/ml (A) and 0.4 ug/ml (B) and used for IP at 6 ug/mg lysate. CHD1L was also immunoprecipitated by rabbit anti-CHD1L antibody MBS3903624, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 10 seconds (B).
Rabbit Anti-CHD1L Polyclonal Antibody – Cat# MBS3903623

Other Notes

Small volumes of anti-CHD1L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CHD1L purchase

MBS3903623 is an antibody targeting CHD1L. Also known as Rabbit anti-CHD1L Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CHD1L. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
chromodomain-helicase-DNA-binding protein 1-like
NCBI Official Synonym Full Names
chromodomain helicase DNA binding protein 1-like
NCBI Official Symbol
CHD1L
NCBI Official Synonym Symbols
ALC1; CHDL; FLJ22530
UniProt Protein Name
Chromodomain-helicase-DNA-binding protein 1-like
UniProt Synonym Protein Names
Amplified in liver cancer protein 1
UniProt Gene Name
CHD1L
UniProt Synonym Gene Names
ALC1
UniProt Entry Name
CHD1L_HUMAN
NCBI Protein Information
chromodomain-helicase-DNA-binding protein 1-like; OTTHUMP00000016308; amplified in liver cancer 1; amplified in liver cancer protein 1

NCBI Summary for CHD1L

In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1; MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).[supplied by OMIM]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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