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CLIP115 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3903628

CLIP-115 (cytoplasmic linker protein 115) was found to associate with both microtubules and an organelle called the dendritic lamellar body. The CLIP-115 protein is encoded by the CLIP2 gene which is hemizygously deleted in Williams syndrome, a multisystem… More details

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Product Overview

Online Datasheet in PDF
Product Name
CLIP115, Polyclonal Antibody
Full Product Name
Rabbit anti-CLIP115 Antibody, Affinity Purified
Product Gene Name
Product Synonym Gene Name
CLIP2
Product Synonym Names
WBSCR4; WSCR4; WSCR3; Williams-Beuren syndrome chromosome region 4; Williams-Beuren syndrome chromosome region 3; williams-Beuren syndrome chromosomal region 4 protein; williams-Beuren syndrome chromosomal region 3 protein; cytoplasmic linker 2; testicular tissue protein Li 40; cytoplasmic linker protein 115; CYLN2; CLIP-115; CLIP; CAP-Gly domain-containing linker protein 2; cytoplasmic linker protein 2; WBSCR3; CAP-Gly domain-containing linker protein 2; CAP-Gly domain containing linker protein 2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
OMIM
603432
3D Structure
ModBase 3D Structure for Q9UDT6
Immunogen
Between 996 and C-terminus
Conjugation
Unconjugated

Product Categories/Family for anti-CLIP115 antibody

Applications Tested/Suitable for anti-CLIP115 antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-CLIP115 antibody
WB: 1:2000-1:10,000
IP: 6ug/mg lysate

Western Blot (WB) of anti-CLIP115 antibody

Detection of human CLIMBS3907998 by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and HEK293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-CLIMBS3907998 antibody MBS3903628 used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. CLIMBS3907998 was also immunoprecipitated by rabbit anti-CLIMBS3907998 antibody MBS3903627, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B).
Rabbit Anti-CLIP115 Polyclonal Antibody – Cat# MBS3903628

Other Notes

Small volumes of anti-CLIP115 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CLIP115 purchase

MBS3903628 is an antibody targeting CLIP115. Also known as Rabbit anti-CLIP115 Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CLIP115. It may not necessarily be applicable to this product.

NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Protein Name
CAP-Gly domain-containing linker protein 2
UniProt Synonym Protein Names
Cytoplasmic linker protein 115; CLIP-115; Cytoplasmic linker protein 2; Williams-Beuren syndrome chromosomal region 3 protein; Williams-Beuren syndrome chromosomal region 4 protein
UniProt Gene Name
CLIP2
UniProt Synonym Gene Names
CYLN2; KIAA0291; WBSCR3; WBSCR4; WSCR4; CLIP-115
UniProt Entry Name
CLIP2_HUMAN

UniProt Comments for CLIP115

CYLN2: Seems to link microtubules to dendritic lamellar body (DLB), a membranous organelle predominantly present in bulbous dendritic appendages of neurons linked by dendrodendritic gap junctions. May operate in the control of brain-specific organelle translocations. CLIP2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of CLIP2 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 7q11.23

Cellular Component: microtubule associated complex; cytoplasmic microtubule

Molecular Function: microtubule plus-end binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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