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CENP-I Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3903655

Centromere protein I (CENP-I) is a component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. CENP-I may be involved in… More details

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Product Overview

Online Datasheet in PDF
Product Name
CENP-I, Polyclonal Antibody
Full Product Name
Rabbit anti-CENP-I Antibody, Affinity Purified
Product Gene Name
Product Synonym Gene Name
CENPI
Product Synonym Names
interphase centromere complex protein 19; FSH primary response 1; LRPR1; leucine-rich primary response protein 1; CENP-I; FSHPRH1; follicle-stimulating hormone primary response protein; centromere protein I; FSH primary response protein 1; Centromere protein I; centromere protein I
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
86,720 Da
Chromosome Location
Chromosome: X; NC_000023.10 (100354798..100417978). Location: Xq22.1
OMIM
300065
3D Structure
ModBase 3D Structure for Q92674
Immunogen
Between 50 and 100
Conjugation
Unconjugated

Product Categories/Family for anti-CENP-I antibody

Applications Tested/Suitable for anti-CENP-I antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-CENP-I antibody
WB: 1:2000-1:10,000
IP: 6ug/mg lysate

Western Blot (WB) of anti-CENP-I antibody

Detection of human CENP-I by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), HEK293T (T; 50 ug) and Jurkat (J; 50 ug) cells. Antibodies: Affinity purified rabbit anti-CENP-I antibody MBS3903655 used for WB at 0.1 ug/ml (A) and 0.4 ug/ml (B) and used for IP at 6 ug/mg lysate. CENP-I was also immunoprecipitated by rabbit anti-CENP-I antibody BL12216, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 30 seconds (A) and 10 seconds (B).
Rabbit Anti-CENP-I Polyclonal Antibody – Cat# MBS3903655

Other Notes

Small volumes of anti-CENP-I antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CENP-I purchase

MBS3903655 is an antibody targeting CENP-I. Also known as Rabbit anti-CENP-I Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CENP-I. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
centromere protein I
NCBI Official Synonym Full Names
centromere protein I
NCBI Official Symbol
CENPI
NCBI Official Synonym Symbols
Mis6; LRPR1; CENP-I; FSHPRH1
UniProt Protein Name
Centromere protein I
UniProt Synonym Protein Names
FSH primary response protein 1; Follicle-stimulating hormone primary response protein; Interphase centromere complex protein 19; Leucine-rich primary response protein 1
Protein Family
UniProt Gene Name
CENPI
UniProt Synonym Gene Names
FSHPRH1; ICEN19; LRPR1; CENP-I
UniProt Entry Name
CENPI_HUMAN
NCBI Protein Information
centromere protein I; FSH primary response 1; FSH primary response protein 1; leucine-rich primary response protein 1; interphase centromere complex protein 19; follicle-stimulating hormone primary response protein

NCBI Summary for CENP-I

The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. This gene is also a potential candidate for human X-linked disorders of gonadal development and gametogenesis. [provided by RefSeq, Jul 2008]

UniProt Comments for CENP-I

CENPI: involved in the response of gonadal tissues to follicle-stimulating hormone. Highly expressed in testis, ovary and spleen.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: Xq22.1

Cellular Component: kinetochore; nucleoplasm; cytoplasm; nucleus; cytosol

Molecular Function: protein binding

Biological Process: nucleosome assembly; DNA replication-independent nucleosome assembly at centromere; mitotic cell cycle; sex differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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