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MUM1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3903656

Mutated melanoma-associated antigen 1 (MUM1) is involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. MUM1 is recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate… More details

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Product Overview

Online Datasheet in PDF
Product Name
MUM1, Polyclonal Antibody
Full Product Name
Rabbit anti-MUM1 Antibody, Affinity Purified
Product Gene Name
Product Synonym Names
MUM-1; PWWP domain-containing protein MUM1; mutated melanoma-associated antigen 1; HSPC211; EXPAND1; protein expandere; melanoma ubiquitous mutated protein; PWWP domain-containing protein MUM1; melanoma associated antigen (mutated) 1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
80,700 Da
3D Structure
ModBase 3D Structure for Q2TAK8
Immunogen
Between 125 and 175
Conjugation
Unconjugated

Product Categories/Family for anti-MUM1 antibody

Applications Tested/Suitable for anti-MUM1 antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-MUM1 antibody
WB: 1:2000-1:10,000
IP: 6ug/mg lysate

Western Blot (WB) of anti-MUM1 antibody

Detection of human MUM1 by western blot and immunoprecipitation. Samples: Whole cell lysate from HEK293T (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), Jurkat (J; 50 ug) and HeLa (H; 50 ug) cells. Antibodies: Affinity purified rabbit anti-MUM1 antibody MBS3903656 used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. MUM1 was also immunoprecipitated by rabbit anti-MUM1 antibody BL12245, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B).
Rabbit Anti-MUM1 Polyclonal Antibody – Cat# MBS3903656

Other Notes

Small volumes of anti-MUM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MUM1 purchase

MBS3903656 is an antibody targeting MUM1. Also known as Rabbit anti-MUM1 Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MUM1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
PWWP domain-containing protein MUM1
NCBI Official Synonym Full Names
melanoma associated antigen (mutated) 1
NCBI Official Symbol
MUM1
NCBI Official Synonym Symbols
MUM-1; EXPAND1; HSPC211
UniProt Protein Name
PWWP domain-containing protein MUM1
UniProt Synonym Protein Names
Mutated melanoma-associated antigen 1; MUM-1; Protein expandere
UniProt Gene Name
MUM1
UniProt Synonym Gene Names
EXPAND1; MUM-1
NCBI Protein Information
PWWP domain-containing protein MUM1

UniProt Comments for MUM1

MUM1: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage. Belongs to the MUM1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell surface

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cytoplasm; nucleus

Molecular Function: nucleosome binding; protein binding

Biological Process: DNA repair; establishment and/or maintenance of chromatin architecture
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MUM1 antibody

 Reference Product  PubMed Publications
 CXCR4 antibody  >1 publications with MUM1 and CXCR4
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