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SRAG Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3903685

SRAG is a small nuclear protein that is characterized by an arginine- and glycine-rich region. SRAG may be involved in cell cycle progression. SRAG interacts with protein arginine methyltransferases and plays a role in the activation of estradiol-dependent… More details

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Product Overview

Online Datasheet in PDF
Product Name
SRAG, Polyclonal Antibody
Full Product Name
Rabbit anti-SRAG Antibody, Affinity Purified
Product Gene Name
Product Synonym Gene Name
CHTOP
Product Synonym Names
chromatin target of PRMT1 protein; SRAG-3; SRAG; small protein rich in arginine and glycine; Small arginine- and glycine-rich protein; pp7704; friend of PRMT1 protein; FL-SRAG; SRAG-5; C1orf77; C10orf77; FOP; Chromatin target of PRMT1 protein; chromatin target of PRMT1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
21,918 Da
OMIM
614206
3D Structure
ModBase 3D Structure for Q9Y3Y2
Predicted Reactivity
Mouse, Rat, Bovine
Immunogen
Between 198 and C-terminus
Conjugation
Unconjugated

Product Categories/Family for anti-SRAG antibody

Applications Tested/Suitable for anti-SRAG antibody
Western Blot (WB)
Application Notes for anti-SRAG antibody
WB: 1:2000-1:10,000

Western Blot (WB) of anti-SRAG antibody

Detection of human SRAG by western blot. Samples: Whole cell lysate from Jurkat (15 and 50 ug), HEK293T (T; 50 ug) and HeLa (H; 50 ug) cells. Antibody: Affinity purified rabbit anti-SRAG antibody MBS3903685 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Rabbit Anti-SRAG Polyclonal Antibody – Cat# MBS3903685

Other Notes

Small volumes of anti-SRAG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SRAG purchase

MBS3903685 is an antibody targeting SRAG. Also known as Rabbit anti-SRAG Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SRAG. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
chromatin target of PRMT1 protein isoform 1
NCBI Official Synonym Full Names
chromatin target of PRMT1
NCBI Official Symbol
CHTOP
NCBI Official Synonym Symbols
FOP; SRAG; SRAG-3; SRAG-5; pp7704; C1orf77; FL-SRAG
UniProt Protein Name
Chromatin target of PRMT1 protein
UniProt Synonym Protein Names
Friend of PRMT1 protein; Small arginine- and glycine-rich protein; SRAG
UniProt Gene Name
CHTOP
UniProt Synonym Gene Names
C1orf77; FOP; SRAG
UniProt Entry Name
CHTOP_HUMAN
NCBI Protein Information
chromatin target of PRMT1 protein

NCBI Summary for SRAG

This gene encodes a small nuclear protein that is characterized by an arginine and glycine rich region. This protein may have an important role in the regulation of fetal globin gene expression and in the activation of estrogen-responsive genes. A recent study reported that this protein binds 5-hydroxymethylcytosine (5hmC) and associates with an arginine methyltransferase complex (methylosome), which promotes methylation of arginine 3 of histone H4 (H4R3) and activation of genes involved in glioblastomagenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2015]
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UniProt Comments for SRAG

CHTOP: Plays an important role in the ligand-dependent activation of estrogen receptor target genes. May play a role in the silencing of fetal globin genes. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Nucleolus

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: intracellular membrane-bound organelle; nuclear speck; nucleolus; nucleoplasm

Molecular Function: methyl-CpG binding; protein binding

Biological Process: mRNA export from nucleus; positive regulation of ATPase activity; positive regulation of cell proliferation; positive regulation of helicase activity; positive regulation of histone methylation; regulation of transcription, DNA-dependent; transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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