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SLBP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3904205

Stem-loop-binding protein (SLBP) is an RNA-binding protein involved in the histone pre-mRNA processing. SLBP binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3'-end processing by stabilizing the complex… More details

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Product Documentation
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SLBP, Polyclonal Antibody
Full Product Name
Rabbit anti-SLBP Antibody, Affinity Purified
Product Gene Name
anti-SLBP antibody
Product Synonym Names
histone binding protein; stem-loop (histone) binding protein; Histone stem-loop-binding protein; histone RNA hairpin-binding protein; HBP; hairpin binding protein, histone; histone stem-loop binding protein; Histone RNA hairpin-binding protein; stem-loop binding protein
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
31,286 Da
OMIM
602422
3D Structure
ModBase 3D Structure for Q14493
Immunogen
Between 220 and C-terminus
Conjugation
Unconjugated

Product Categories/Family for anti-SLBP antibody

Primary Antibodies
Applications Tested/Suitable for anti-SLBP antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-SLBP antibody
WB: 1:1000-1:5000
IP: 6ug/mg lysate

Immunoprecipitation (IP) of anti-SLBP antibody

Detection of human SLBP by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from HEK293T cells. Antibodies: Affinity purified rabbit anti-SLBP antibody MBS3904205 (lot MBS3904205-1) used for IP at 6 ug/mg lysate. SLBP was also immunoprecipitated by rabbit anti-SLBP antibody BL14232. For blotting immunoprecipitated SLBP, MBS3904205 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Rabbit Anti-SLBP Polyclonal Antibody – Cat# MBS3904205

Western Blot (WB) of anti-SLBP antibody

Detection of human SLBP by western blot. Samples: Whole cell lysate (50 ug) from HEK293T, HeLa, and Jurkat cells. Antibodies: Affinity purified rabbit anti-SLBP antibody MBS3904205 (lot MBS3904205-1) used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Rabbit Anti-SLBP Polyclonal Antibody, Western Blot (WB) – Cat# MBS3904205

Other Notes

Small volumes of anti-SLBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLBP purchase

MBS3904205 is an antibody targeting SLBP. Also known as Rabbit anti-SLBP Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLBP. It may not necessarily be applicable to this product.

NCBI GI #
5729862
NCBI GeneID
7884
NCBI Accession #
NP_006518.1
UniProt Primary Accession #
Q14493
UniProt Secondary Accession #
B3KRJ5
UniProt Related Accession #
Q14493
GenBank Nucleotide #
NM_006527.2
NCBI Official Full Name
histone RNA hairpin-binding protein
NCBI Official Synonym Full Names
stem-loop binding protein
NCBI Official Symbol
SLBP
NCBI Official Synonym Symbols
HBP
UniProt Protein Name
Histone RNA hairpin-binding protein
UniProt Synonym Protein Names
Histone stem-loop-binding protein
UniProt Gene Name
SLBP
UniProt Synonym Gene Names
HBP
UniProt Entry Name
SLBP_HUMAN
NCBI Protein Information
histone RNA hairpin-binding protein; histone binding protein; hairpin binding protein, histone; histone stem-loop binding protein; histone stem-loop-binding protein; stem-loop (histone) binding protein

NCBI Summary for SLBP

This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1. [provided by RefSeq, Jul 2008]
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Research Articles on SLBP

1. C-terminal extension of Lsm4 interacts directly with the histone mRNP, contacting both SLBP and 3'hExo.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLBP antibody

 Reference Product  PubMed Publications
 ZNF473 antibody  >3 publications with SLBP and ZNF473
 LSM10 antibody  >3 publications with SLBP and LSM10

Pathways associated with anti-SLBP antibody

 Products by Pathway  Pathway Diagram
 Cleavage Of Growing Transcript In The Termination Region Pathway antibodies  Cleavage Of Growing Transcript In The Termination Region Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies  Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
 Processing Of Capped Intronless Pre-mRNA Pathway antibodies  Processing Of Capped Intronless Pre-mRNA Pathway Diagram
 RNA Polymerase II Transcription Pathway antibodies  RNA Polymerase II Transcription Pathway Diagram
 RNA Polymerase II Transcription Termination Pathway antibodies  RNA Polymerase II Transcription Termination Pathway Diagram
 SLBP Dependent Processing Of Replication-Dependent Histone Pre-mRNAs Pathway antibodies  SLBP Dependent Processing Of Replication-Dependent Histone Pre-mRNAs Pathway Diagram
 Transport Of Mature Transcript To Cytoplasm Pathway antibodies  Transport Of Mature Transcript To Cytoplasm Pathway Diagram
 Transport Of Mature MRNAs Derived From Intronless Transcripts Pathway antibodies  Transport Of Mature MRNAs Derived From Intronless Transcripts Pathway Diagram
 Transport Of The SLBP Dependant Mature MRNA Pathway antibodies  Transport Of The SLBP Dependant Mature MRNA Pathway Diagram

Diseases associated with anti-SLBP antibody

 Disease Name  Pubmed Publications
 Death Antibodies  >2 publications with SLBP and Death
 Neoplasms Antibodies  >2 publications with SLBP and Neoplasms
 Cardiovascular Diseases Antibodies  >1 publications with SLBP and Cardiovascular Diseases
 Immune System Diseases Antibodies  >1 publications with SLBP and Immune System Diseases
 Carcinoma Antibodies  >1 publications with SLBP and Carcinoma
 Vascular Diseases Antibodies  >1 publications with SLBP and Vascular Diseases
 Drug Toxicity Antibodies  >1 publications with SLBP and Drug Toxicity
 Infertility, Female Antibodies  >1 publications with SLBP and Infertility, Female
 Necrosis Antibodies  >1 publications with SLBP and Necrosis

Organs/Tissues associated with anti-SLBP antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >2 publications with SLBP and Muscle
 Blood Antibodies  >2 publications with SLBP and Blood
 Bone Antibodies  >1 publications with SLBP and Bone
 Spleen Antibodies  >1 publications with SLBP and Spleen
 Stomach Antibodies  >1 publications with SLBP and Stomach
 Liver Antibodies  >1 publications with SLBP and Liver
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