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TIMM8A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3904234

Translocase of inner mitochondrial membrane 8 homolog A (TIMM8A) is a translocase involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The TIMM8A gene is mutated in Mohr-Tranebjaerg… More details

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Product Overview

Online Datasheet in PDF
Product Name
TIMM8A, Polyclonal Antibody
Full Product Name
Rabbit anti-TIMM8A Antibody, Affinity Purified
Product Gene Name
Product Synonym Names
DDP1; translocase of inner mitochondrial membrane 8 homolog A; MTS; TIM8; X-linked deafness dystonia protein; DFN1; deafness dystonia protein 1; DDP; mitochondrial import inner membrane translocase subunit Tim8 A; deafness/dystonia peptide; Mitochondrial import inner membrane translocase subunit Tim8 A; translocase of inner mitochondrial membrane 8A
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
10,998 Da
OMIM
U66035 mRNA
3D Structure
ModBase 3D Structure for O60220
Immunogen
Between 1 and 50
Conjugation
Unconjugated

Product Categories/Family for anti-TIMM8A antibody

Applications Tested/Suitable for anti-TIMM8A antibody
Immunoprecipitation (IP)
Application Notes for anti-TIMM8A antibody
IP: 6ug/mg lysate

Immunoprecipitation (IP) of anti-TIMM8A antibody

Detection of human TIMM8A by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from HEK293T cells. Antibodies: Affinity purified rabbit anti-TIMM8A antibody MBS3904234 (lot MBS3904234-1) used for IP at 6 ug/mg lysate. TIMM8A was also immunoprecipitated by rabbit anti-TIMM8A antibody BL14392. For blotting immunoprecipitated TIMM8A, MBS3904234 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Rabbit Anti-TIMM8A Polyclonal Antibody – Cat# MBS3904234

Other Notes

Small volumes of anti-TIMM8A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TIMM8A purchase

MBS3904234 is an antibody targeting TIMM8A. Also known as Rabbit anti-TIMM8A Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TIMM8A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
mitochondrial import inner membrane translocase subunit Tim8 A isoform 1
NCBI Official Synonym Full Names
translocase of inner mitochondrial membrane 8 homolog A (yeast)
NCBI Official Symbol
TIMM8A
NCBI Official Synonym Symbols
DDP; MTS; DDP1; DFN1; TIM8
UniProt Protein Name
Mitochondrial import inner membrane translocase subunit Tim8 A
UniProt Synonym Protein Names
Deafness dystonia protein 1; X-linked deafness dystonia protein
UniProt Gene Name
TIMM8A
UniProt Synonym Gene Names
DDP; DDP1; TIM8A
NCBI Protein Information
mitochondrial import inner membrane translocase subunit Tim8 A; deafness/dystonia peptide; deafness dystonia protein 1; X-linked deafness dystonia protein

UniProt Comments for TIMM8A

Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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