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TMX1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3904267

Thioredoxin-related transmembrane protein 1 (TMX1) may participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions [taken from the Universal Protein… More details

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Product Overview

Online Datasheet in PDF
Product Name
TMX1, Polyclonal Antibody
Full Product Name
Rabbit anti-TMX1 Antibody, Affinity Purified
Product Gene Name
Product Synonym Names
TMX; TXNDC; TXNDC1; transmembrane Trx-related protein; thioredoxin domain-containing protein 1; thioredoxin domain containing 1; PDIA11; protein disulfide isomerase family A, member 11; thioredoxin-related transmembrane protein 1; Thioredoxin-related transmembrane protein 1; thioredoxin related transmembrane protein 1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
31,791 Da
OMIM
610527
3D Structure
ModBase 3D Structure for Q9H3N1
Immunogen
Between 230 and C-terminus
Conjugation
Unconjugated

Product Categories/Family for anti-TMX1 antibody

Applications Tested/Suitable for anti-TMX1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TMX1 antibody
WB: 1:2000-1:10,000
IHC: 1:500-1:2000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Immunohistochemistry (IHC) of anti-TMX1 antibody

Detection of human TMX1 by immunohistochemistry. Sample: FFPE section of human breast carcinoma (glands). Antibody: Affinity purified rabbit anti-TMX1 (Cat. No. MBS3904267 Lot1) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB. Counterstain: IHC Hematoxylin (blue).
Rabbit Anti-TMX1 Polyclonal Antibody – Cat# MBS3904267

Western Blot (WB) of anti-TMX1 antibody

Detection of human TMX1 by western blot. Samples: Whole cell lysate (50 ug) from Jurkat, HEK293T, and HeLa cells. Antibodies: Affinity purified rabbit anti-TMX1 antibody MBS3904267 (lot MBS3904267-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Rabbit Anti-TMX1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3904267

Other Notes

Small volumes of anti-TMX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TMX1 purchase

MBS3904267 is an antibody targeting TMX1. Also known as Rabbit anti-TMX1 Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TMX1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
thioredoxin-related transmembrane protein 1
NCBI Official Synonym Full Names
thioredoxin-related transmembrane protein 1
NCBI Official Symbol
TMX1
NCBI Official Synonym Symbols
TMX; TXNDC; PDIA11; TXNDC1
UniProt Protein Name
Thioredoxin-related transmembrane protein 1
UniProt Synonym Protein Names
Thioredoxin domain-containing protein 1; Transmembrane Trx-related protein
UniProt Gene Name
TMX1
UniProt Synonym Gene Names
TMX; TXNDC; TXNDC1
UniProt Entry Name
TMX1_HUMAN
NCBI Protein Information
thioredoxin-related transmembrane protein 1; protein disulfide isomerase family A, member 11; thioredoxin domain containing 1; thioredoxin domain-containing protein 1; transmembrane Trx-related protein

NCBI Summary for TMX1

TXNDC1 is a thioredoxin (TXN; see MIM 187700)-related protein with disulfide reductase activity (Matsuo et al., 2001 [PubMed 11152479]).[supplied by OMIM, Mar 2008]

UniProt Comments for TMX1

TXNDC1: May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 14q22.1

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; nucleolus; integral to membrane

Molecular Function: disulfide oxidoreductase activity; protein disulfide isomerase activity

Biological Process: protein folding; cell redox homeostasis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-TMX1 antibody

Organs/Tissues associated with anti-TMX1 antibody

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