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LUC7L2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3904711

Putative RNA-binding protein Luc7-like 2 (LUC7L2) may bind to RNA via its Arg/Ser-rich domain [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y383]. More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
LUC7L2, Polyclonal Antibody
Full Product Name
Rabbit anti-LUC7L2 Antibody, Affinity Purified
Product Gene Name
anti-LUC7L2 antibody
Product Synonym Names
putative RNA-binding protein Luc7-like 2; LUC7-like 2; CGI-59; CGI-74; LUC7B2; Putative RNA-binding protein Luc7-like 2; LUC7 like 2, pre-mRNA splicing factor
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
46,229 Da
OMIM
613056
3D Structure
ModBase 3D Structure for Q9Y383
Predicted Reactivity
Mouse
Immunogen
Between 342 and C-terminus
Conjugation
Unconjugated

Product Categories/Family for anti-LUC7L2 antibody

Primary Antibodies
Applications Tested/Suitable for anti-LUC7L2 antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-LUC7L2 antibody
WB: 1:10,000-1:25,000
IP: 6ug/mg lysate

Immunoprecipitation (IP) of anti-LUC7L2 antibody

Detection of human LUC7L2 by western blot of immunoprecipitates. Samples: Whole cell lysate (1.0 mg per IP reaction; 10% of IP loaded) from HEK293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-LUC7L2 antibody (MBS3904711 lot 3) used for IP at 6 ug per reaction. LUC7L2 was also immunoprecipitated by a previous lot of this antibody (MBS3904711 lot 2) and a second antibody against a different epitope of LUC7L2 (BL17197). For blotting immunoprecipitated LUC7L2, MBS3904711 was used at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 1 second.
Rabbit Anti-LUC7L2 Polyclonal Antibody – Cat# MBS3904711

Western Blot (WB) of anti-LUC7L2 antibody

Detection of human LUC7L2 by western blot. Samples: Whole cell lysate (10 ug) from HEK293T, HeLa, Jurkat, K-562, and LNCaP cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-LUC7L2 antibody (MBS3904711 lot 3) used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
Rabbit Anti-LUC7L2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3904711

Other Notes

Small volumes of anti-LUC7L2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LUC7L2 purchase

MBS3904711 is an antibody targeting LUC7L2. Also known as Rabbit anti-LUC7L2 Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LUC7L2. It may not necessarily be applicable to this product.

NCBI GI #
116812577
NCBI GeneID
51631
NCBI Accession #
NP_057103.2
UniProt Primary Accession #
Q9Y383
UniProt Secondary Accession #
Q8IUP9; Q9NVL3; Q9NVN7; Q9UQN1; B7Z500
UniProt Related Accession #
Q9Y383
GenBank Nucleotide #
NM_016019.4
NCBI Official Full Name
putative RNA-binding protein Luc7-like 2 isoform 1
NCBI Official Synonym Full Names
LUC7-like 2 pre-mRNA splicing factor
NCBI Official Symbol
LUC7L2
NCBI Official Synonym Symbols
CGI-59; CGI-74; LUC7B2
UniProt Protein Name
Putative RNA-binding protein Luc7-like 2
Protein Family
Putative RNA-binding protein
UniProt Gene Name
LUC7L2
UniProt Entry Name
LC7L2_HUMAN
NCBI Protein Information
putative RNA-binding protein Luc7-like 2

NCBI Summary for LUC7L2

This gene encodes a protein that contains a C2H2-type zinc finger, coiled-coil region and arginine, serine-rich (RS) domain. A similar protein in mouse interacts with sodium channel modifier 1, and the encoded protein may be involved in the recognition of non-consensus splice donor sites in association with the U1 snRNP spliceosomal subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
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UniProt Comments for LUC7L2

LUC7L2: a Luc7 family protein that may bind RNA via its Arg/Ser-rich domain. Contains 1 C2H2-type zinc finger. Two alternatively spliced isoforms have been described.

Protein type: C2H2-type zinc finger protein; RNA-binding

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: nuclear speck; snRNP U1

Molecular Function: mRNA binding; protein binding; enzyme binding

Biological Process: mRNA splice site selection
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Research Articles on LUC7L2

1. Loss of LUC7L2 is associated with myeloid neoplasms.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LUC7L2 antibody

 Reference Product  PubMed Publications
 SCNM1 antibody  >1 publications with LUC7L2 and SCNM1

Organs/Tissues associated with anti-LUC7L2 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with LUC7L2 and Blood
 Bone Antibodies  >1 publications with LUC7L2 and Bone
 Bone Marrow Antibodies  >1 publications with LUC7L2 and Bone Marrow
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