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OGFR Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3904713

Opioid growth factor receptor (OGFR) is a receptor for opioid growth factor (OGF), also known as Met-enkephalin. OGFR seems to be involved in growth regulation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NZT2]. More details

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Product Overview

Online Datasheet in PDF
Product Name
OGFR, Polyclonal Antibody
Full Product Name
Rabbit anti-OGFR Antibody, Affinity Purified
Product Gene Name
Product Synonym Names
OGFr; opioid growth factor receptor; protein 7-60; zeta-type opioid receptor; Opioid growth factor receptor; opioid growth factor receptor
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
73,325 Da
Chromosome Location
Chromosome: 20; NC_000020.10 (61436177..61445352). Location: 20q13.3
OMIM
606459
3D Structure
ModBase 3D Structure for Q9NZT2
Immunogen
Between 627 and C-terminus
Conjugation
Unconjugated

Product Categories/Family for anti-OGFR antibody

Applications Tested/Suitable for anti-OGFR antibody
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
Application Notes for anti-OGFR antibody
WB: 1:2000-1:10,000
IP: 6ug/mg lysate
IHC: 1:500-1:2000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Immunohistochemistry (IHC) of anti-OGFR antibody

Detection of human OGFR by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-OGFR (Cat. No. MBS3904713 Lot1) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB
Rabbit Anti-OGFR Polyclonal Antibody – Cat# MBS3904713

Immunoprecipitation (IP) of anti-OGFR antibody

Detection of human OGFR by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-OGFR antibody MBS3904713 (lot MBS3904713-1) used for IP at 6 ug per reaction. OGFR was also immunoprecipitated by rabbit anti-OGFR antibody BL17209. For blotting immunoprecipitated OGFR, MBS3904713 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Rabbit Anti-OGFR Polyclonal Antibody, Immunoprecipitation (IP) – Cat# MBS3904713

Western Blot (WB) of anti-OGFR antibody

Detection of human OGFR by western blot. Samples: Whole cell lysate (50 ug) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-OGFR antibody MBS3904713 (lot MBS3904713-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Rabbit Anti-OGFR Polyclonal Antibody, Western Blot (WB) – Cat# MBS3904713

Other Notes

Small volumes of anti-OGFR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OGFR purchase

MBS3904713 is an antibody targeting OGFR. Also known as Rabbit anti-OGFR Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for OGFR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
opioid growth factor receptor
NCBI Official Synonym Full Names
opioid growth factor receptor
NCBI Official Symbol
OGFR
UniProt Protein Name
Opioid growth factor receptor
UniProt Synonym Protein Names
Protein 7-60; Zeta-type opioid receptor
UniProt Gene Name
OGFR
UniProt Synonym Gene Names
OGFr
UniProt Entry Name
OGFR_HUMAN
NCBI Protein Information
opioid growth factor receptor; 7-60 protein; protein 7-60; zeta-type opioid receptor

NCBI Summary for OGFR

The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. [provided by RefSeq, Jul 2008]
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UniProt Comments for OGFR

OGFR: Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation. Belongs to the opioid growth factor receptor family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.

Chromosomal Location of Human Ortholog: 20q13.3

Cellular Component: membrane; cytoplasm; nucleus

Molecular Function: opioid receptor activity

Biological Process: regulation of cell growth
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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