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LL5beta Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3904752

Pleckstrin homology-like domain family B member 2 (LL5beata) seems to be involved in the assembly of the postsynaptic apparatus. LL5beta may play a role in acetyl-choline receptor (AChR) aggregation in the postsynaptic membrane (By similarity) [taken from… More details

$250 / 0.01 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
LL5beta, Polyclonal Antibody
Full Product Name
Rabbit anti-LL5beta Antibody, Affinity Purified
Product Gene Name
Product Synonym Gene Name
PHLDB2
Product Synonym Names
LL5 beta; LL5b; LL5beta; pleckstrin homology-like domain family B member 2; protein LL5-beta; Pleckstrin homology-like domain family B member 2; pleckstrin homology like domain family B member 2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
OMIM
AJ496194 mRNA
3D Structure
ModBase 3D Structure for Q86SQ0
Immunogen
Between 250 and 300
Conjugation
Unconjugated

Product Categories/Family for anti-LL5beta antibody

Applications Tested/Suitable for anti-LL5beta antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-LL5beta antibody
WB: 1:2000-1:10,000
IP: 6ug/mg lysate

Immunoprecipitation (IP) of anti-LL5beta antibody

Detection of human LL5beta by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-LL5beta antibody MBS3904752 (lot MBS3904752-1) used for IP at 6 ug per reaction. LL5beta was also immunoprecipitated by rabbit anti-LL5beta antibody BL17347. For blotting immunoprecipitated LL5beta, MBS3904752 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Rabbit Anti-LL5beta Polyclonal Antibody – Cat# MBS3904752

Western Blot (WB) of anti-LL5beta antibody

Detection of human LL5beta by western blot. Samples: Whole cell lysate (50 ug) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-LL5beta antibody MBS3904752 (lot MBS3904752-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Rabbit Anti-LL5beta Polyclonal Antibody, Western Blot (WB) – Cat# MBS3904752

Other Notes

Small volumes of anti-LL5beta antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LL5beta purchase

MBS3904752 is an antibody targeting LL5beta. Also known as Rabbit anti-LL5beta Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LL5beta. It may not necessarily be applicable to this product.

NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Protein Name
Pleckstrin homology-like domain family B member 2
UniProt Synonym Protein Names
Protein LL5-beta
UniProt Gene Name
PHLDB2
UniProt Synonym Gene Names
LL5B

UniProt Comments for LL5beta

PHLDB2: Seems to be involved in the assembly of the postsynaptic apparatus. May play a role in acetyl-choline receptor (AChR) aggregation in the postsynaptic membrane. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 3q13.2

Cellular Component: basal cortex; cell leading edge; cytosol; focal adhesion; intermediate filament cytoskeleton; plasma membrane

Molecular Function: cadherin binding; protein binding

Biological Process: establishment of protein localization; microtubule cytoskeleton organization; negative regulation of focal adhesion assembly; negative regulation of stress fiber formation; positive regulation of basement membrane assembly involved in embryonic body morphogenesis; regulation of epithelial to mesenchymal transition; regulation of gastrulation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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