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FLN29 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3904844

FLN29 is a negative feedback regulator that controls excessive innate immune responses. It regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. FLN29 may inhibit the LTR pathway by direct interaction with TRAF6 and… More details

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Product Overview

Online Datasheet in PDF
Product Name
FLN29, Polyclonal Antibody
Full Product Name
Rabbit anti-FLN29 Antibody, Affinity Purified
Product Gene Name
Product Synonym Gene Name
TRAFD1
Product Synonym Names
FLN29; FLN29 gene product; Protein FLN29; TRAF-type zinc finger domain-containing protein 1; TRAF-type zinc finger domain-containing protein 1; TRAF-type zinc finger domain containing 1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
19,034 Da
OMIM
AB007447 mRNA
3D Structure
ModBase 3D Structure for O14545
Immunogen
Between 1 and 50
Conjugation
Unconjugated

Product Categories/Family for anti-FLN29 antibody

Applications Tested/Suitable for anti-FLN29 antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-FLN29 antibody
WB: 1:2000-1:10,000
IP: 6ug/mg lysate

Immunoprecipitation (IP) of anti-FLN29 antibody

Detection of human FLN29 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-FLN29 antibody MBS3904844 (lot MBS3904844-1) used for IP at 6 ug per reaction. FLN29 was also immunoprecipitated by rabbit anti-FLN29 antibody BL17941. For blotting immunoprecipitated FLN29, MBS3904844 was used at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Rabbit Anti-FLN29 Polyclonal Antibody – Cat# MBS3904844

Western Blot (WB) of anti-FLN29 antibody

Detection of human FLN29 by western blot. Samples: Whole cell lysate (50 ug) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-FLN29 antibody MBS3904844 (lot MBS3904844-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Rabbit Anti-FLN29 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3904844

Other Notes

Small volumes of anti-FLN29 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FLN29 purchase

MBS3904844 is an antibody targeting FLN29. Also known as Rabbit anti-FLN29 Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FLN29. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
TRAF-type zinc finger domain-containing protein 1
NCBI Official Synonym Full Names
TRAF-type zinc finger domain containing 1
NCBI Official Symbol
TRAFD1
NCBI Official Synonym Symbols
FLN29
UniProt Protein Name
TRAF-type zinc finger domain-containing protein 1
UniProt Synonym Protein Names
Protein FLN29
UniProt Gene Name
TRAFD1
UniProt Synonym Gene Names
FLN29
NCBI Protein Information
TRAF-type zinc finger domain-containing protein 1

NCBI Summary for FLN29

The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses (Sanada et al., 2008 [PubMed 18849341]).[supplied by OMIM, Dec 2009]

UniProt Comments for FLN29

Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FLN29 antibody

Diseases associated with anti-FLN29 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >2 publications with FLN29 and Necrosis
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