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VTA1/LIP5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3904994

VTA1 is involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling… More details

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Product Overview

Online Datasheet in PDF
Product Name
VTA1/LIP5, Polyclonal Antibody
Full Product Name
Rabbit anti-VTA1/LIP5 Antibody, Affinity Purified
Product Gene Name
anti-VTA1/LIP5 antibody
Product Synonym Gene Name
VTA1
Product Synonym Names
LIP5; vesicle (multivesicular body) trafficking 1; vacuolar protein sorting-associated protein VTA1 homolog; SKD1-binding protein 1; SBP1; LYST-interacting protein 5; Vps20-associated 1 homolog; HSPC228; homolog of mouse SKD1-binding protein 1; DRG-1; DRG1; dopamine-responsive gene 1 protein; C6orf55; My012; Vacuolar protein sorting-associated protein VTA1 homolog; vesicle trafficking 1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
36.5 kDa
OMIM
610902
3D Structure
ModBase 3D Structure for Q9NP79
Immunogen
Between 257 and C-terminus
Conjugation
Unconjugated

Product Categories/Family for anti-VTA1/LIP5 antibody

Primary Antibodies
Applications Tested/Suitable for anti-VTA1/LIP5 antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-VTA1/LIP5 antibody
WB: 1:2000-1:10,000
IP: 6ug/mg lysate

Immunoprecipitation (IP) of anti-VTA1/LIP5 antibody

Detection of human VTA1/LIP5 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-VTA1/LIP5 antibody MBS3904994 (lot MBS3904994-1) used for IP at 6 ug per reaction. VTA1/LIP5 was also immunoprecipitated by rabbit anti-VTA1/LIP5 antibody MBS3904993. For blotting immunoprecipitated VTA1/LIP5, MBS3904994 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
Rabbit Anti-VTA1/LIP5 Polyclonal Antibody – Cat# MBS3904994

Western Blot (WB) of anti-VTA1/LIP5 antibody

Detection of human VTA1/LIP5 by western blot. Samples: Whole cell lysate (50 ug) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-VTA1/LIP5 antibody MBS3904994 (lot MBS3904994-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Rabbit Anti-VTA1/LIP5 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3904994

Other Notes

Small volumes of anti-VTA1/LIP5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VTA1/LIP5 purchase

MBS3904994 is an antibody targeting VTA1/LIP5. Also known as Rabbit anti-VTA1/LIP5 Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for VTA1/LIP5. It may not necessarily be applicable to this product.

NCBI GI #
21361741
NCBI GeneID
51534
NCBI Accession #
NP_057569.2
UniProt Primary Accession #
Q9NP79
UniProt Secondary Accession #
Q5TGM1; Q6IAE8; Q9H0R2; Q9H3K9; Q9P0Q0; B4DW55; E1P594; E7ETQ7
UniProt Related Accession #
Q9NP79
GenBank Nucleotide #
NM_016485.3
NCBI Official Full Name
vacuolar protein sorting-associated protein VTA1 homolog isoform a
NCBI Official Synonym Full Names
vesicle (multivesicular body) trafficking 1
NCBI Official Symbol
VTA1
NCBI Official Synonym Symbols
DRG1; LIP5; SBP1; DRG-1; My012; C6orf55; HSPC228
UniProt Protein Name
Vacuolar protein sorting-associated protein VTA1 homolog
UniProt Synonym Protein Names
Dopamine-responsive gene 1 protein; DRG-1; LYST-interacting protein 5; LIP5; SKD1-binding protein 1; SBP1
UniProt Gene Name
VTA1
UniProt Synonym Gene Names
C6orf55; DRG-1; LIP5; SBP1
UniProt Entry Name
VTA1_HUMAN
NCBI Protein Information
vacuolar protein sorting-associated protein VTA1 homolog

UniProt Comments for VTA1/LIP5

VTA1: Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR. Involved in HIV-1 budding. Belongs to the VTA1 family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 6q24.1

Cellular Component: endosome membrane; cytosol

Molecular Function: protein binding

Biological Process: protein transport; viral reproduction; viral infectious cycle; endosome transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-VTA1/LIP5 antibody

 Reference Product  PubMed Publications
 VPS4A antibody  >5 publications with VTA1/LIP5 and VPS4A
 CHMP5 antibody  >5 publications with VTA1/LIP5 and CHMP5
 CHMP1B antibody  >3 publications with VTA1/LIP5 and CHMP1B
 VPS4B antibody  >3 publications with VTA1/LIP5 and VPS4B
 CHMP4A antibody  >2 publications with VTA1/LIP5 and CHMP4A
 CHMP2A antibody  >2 publications with VTA1/LIP5 and CHMP2A
 CHMP4B antibody  >1 publications with VTA1/LIP5 and CHMP4B
 CHMP3 antibody  >1 publications with VTA1/LIP5 and CHMP3
 CHMP6 antibody  >1 publications with VTA1/LIP5 and CHMP6

Pathways associated with anti-VTA1/LIP5 antibody

 Products by Pathway  Pathway Diagram
 Budding And Maturation Of HIV Virion Pathway antibodies  Budding And Maturation Of HIV Virion Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endosomal Sorting Complex Required For Transport (ESCRT) Pathway antibodies  Endosomal Sorting Complex Required For Transport (ESCRT) Pathway Diagram
 HIV Infection Pathway antibodies  HIV Infection Pathway Diagram
 HIV Life Cycle Pathway antibodies  HIV Life Cycle Pathway Diagram
 Infectious Disease Pathway antibodies  Infectious Disease Pathway Diagram
 Late Phase Of HIV Life Cycle Pathway antibodies  Late Phase Of HIV Life Cycle Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram

Diseases associated with anti-VTA1/LIP5 antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >4 publications with VTA1/LIP5 and Kidney Diseases
 Cardiovascular Diseases Antibodies  >1 publications with VTA1/LIP5 and Cardiovascular Diseases
 Hypertension Antibodies  >1 publications with VTA1/LIP5 and Hypertension
 Heart Diseases Antibodies  >1 publications with VTA1/LIP5 and Heart Diseases

Organs/Tissues associated with anti-VTA1/LIP5 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >6 publications with VTA1/LIP5 and Kidney
 Vascular Antibodies  >1 publications with VTA1/LIP5 and Vascular
 Blood Antibodies  >1 publications with VTA1/LIP5 and Blood
 Prostate Antibodies  >1 publications with VTA1/LIP5 and Prostate
 Heart Antibodies  >1 publications with VTA1/LIP5 and Heart
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