Rabbit Anti-SCYL2 Polyclonal Antibody – Cat# MBS3905041

Detection of human and mouse SCYL2 by western blot. Samples: Whole cell lysate (50 ug) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-SCYL2 antibody MBS3905041 (lot MBS3905041-1) used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

SCYL2 Antibody – Rabbit Polyclonal

Name: SCYL2 Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS3905041
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3905041

SCY1-like protein 2 (SCYL2) is a component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. According to PubMed:15809293, it is a probable serine/threonine-protein kinase that phosphorylates, in vitro, the… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SCYL2, Polyclonal Antibody

Full Product Name

Rabbit anti-SCYL2 Antibody, Affinity Purified

Product Gene Name

anti-SCYL2 antibody

Product Synonym Names

coated vesicle-associated kinase of 104 kDa; CVAK104; SCY1-like 2; SCY1-like protein 2; SCY1-like, kinase-like 2; SCY1-like protein 2; SCY1 like pseudokinase 2

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human, Mouse

Form/Format

Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Purity/Purification

Antigen Affinity Purified

Concentration

1000ug/ml (lot specific)

Preparation and Storage

Store at 2-8 degree C
Shelf Life: 1 year from date of receipt

Molecular Weight

103,709 Da

Chromosome Location

Chromosome: 12; NC_000012.11 (100661549..100733917). Location: 12q23.1

OMIM

AK001597 mRNA

3D Structure

ModBase 3D Structure for Q6P3W7

Immunogen

Between 825 and 875

Conjugation

Unconjugated

Product Categories/Family for anti-SCYL2 antibody

Primary Antibodies

Applications Tested/Suitable for anti-SCYL2 antibody

Western Blot (WB)

Application Notes for anti-SCYL2 antibody

WB: 1:10,000-1:25,000

Other Notes

Small volumes of anti-SCYL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SCYL2 purchase

MBS3905041 is an antibody targeting SCYL2. Also known as Rabbit anti-SCYL2 Antibody, Affinity Purified. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SCYL2. It may not necessarily be applicable to this product.

NCBI GI #

47604944

NCBI GeneID

55681

NCBI Accession #

NP_060458.3

UniProt Primary Accession #

Q6P3W7

UniProt Secondary Accession #

Q96EF4; Q96ST4; Q9H7V5; Q9NVH3; Q9P2I7; A8KAB5

UniProt Related Accession #

Q6P3W7; Q9NWE9

GenBank Nucleotide #

NM_017988.4

NCBI Official Full Name

SCY1-like protein 2

NCBI Official Synonym Full Names

SCY1-like 2 (S. cerevisiae)

NCBI Official Symbol

SCYL2

NCBI Official Synonym Symbols

CVAK104; FLJ10074; KIAA1360

UniProt Protein Name

SCY1-like protein 2

UniProt Synonym Protein Names

Coated vesicle-associated kinase of 104 kDa

Protein Family

SCY1-like protein

UniProt Gene Name

SCYL2

UniProt Synonym Gene Names

CVAK104; KIAA1360

NCBI Protein Information

SCY1-like protein 2; coated vesicle-associated kinase of 104 kDa

UniProt Comments for SCYL2

SCYL2: Component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. According to PubMed:15809293, probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L- lysine. According to PubMed:16914521, has no detectable kinase activity in vitro. May regulate clathrin-dependent trafficking between the TGN and/or the endosomal system. Belongs to the protein kinase superfamily.

Protein type: Kinase, protein; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); SCY1 family

Chromosomal Location of Human Ortholog: 12q23.1

Molecular Function: protein binding; receptor binding

Biological Process: endosome to lysosome transport; positive regulation of receptor internalization

Research Articles on SCYL2

1. Studies identify CVAK104 as a novel binding partner of Dishevelled (Dvl) and that CVAK104 also interacts with Fzd5.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-SCYL2 antibody

Disease Name	Pubmed Publications
Edema Antibodies	>1 publications with SCYL2 and Edema

Organs/Tissues associated with anti-SCYL2 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>1 publications with SCYL2 and Brain