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LTBR Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3905304

Tumor necrosis factor receptor superfamily member 3, also known as lymphotoxin-beta receptor, is encoded for by the gene LTBR. A member of the tumor necrosis factor receptor superfamily, the major ligands of this receptor include lymphotoxin alpha/beta and… More details

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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
LTBR/Lymphotoxin-beta Receptor, Polyclonal Antibody
Full Product Name
Rabbit anti-LTBR/Lymphotoxin-beta Receptor Antibody, Affinity Purified
Product Gene Name
Product Synonym Names
TNF-R-III; TNFR2-RP; tumor necrosis factor receptor type III; tumor necrosis factor receptor superfamily member 3; tumor necrosis factor receptor 2-related protein; tumor necrosis factor C receptor; TNFRSF3; TNFR-RP; TNFR-III; LT-BETA-R; TNFR3; D12S370; TNFCR; Lymphotoxin-beta receptor; lymphotoxin beta receptor (TNFR superfamily, member 3); lymphotoxin B receptor; TNF-RIII; Tumor necrosis factor receptor superfamily member 3; lymphotoxin beta receptor
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
46,709 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (6493357..6500734). Location: 12p13
OMIM
600979
3D Structure
ModBase 3D Structure for P36941
Immunogen
Between 385 and C-terminus
Conjugation
Unconjugated

Product Categories/Family for anti-LTBR antibody

Applications Tested/Suitable for anti-LTBR antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-LTBR antibody
WB: 1:2000-1:10,000
IP: 6ug/mg lysate

Immunoprecipitation (IP) of anti-LTBR antibody

Detection of human LTBR by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-LTBR antibody MBS3905304 (lot MBS3905304-1) used for IP at 6 ug per reaction. LTBR was also immunoprecipitated by rabbit anti-LTBR antibody MBS3905330. For blotting immunoprecipitated LTBR, MBS3905304 was used at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Rabbit Anti-LTBR Polyclonal Antibody – Cat# MBS3905304

Western Blot (WB) of anti-LTBR antibody

Detection of human LTBR by western blot. Samples: Whole cell lysate (50 ug) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-LTBR antibody MBS3905304 (lot MBS3905304-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Rabbit Anti-LTBR Polyclonal Antibody, Western Blot (WB) – Cat# MBS3905304

Other Notes

Small volumes of anti-LTBR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LTBR purchase

MBS3905304 is an antibody targeting LTBR. Also known as Rabbit anti-LTBR/Lymphotoxin-beta Receptor Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LTBR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 3
NCBI Official Synonym Full Names
lymphotoxin beta receptor (TNFR superfamily, member 3)
NCBI Official Symbol
LTBR
NCBI Official Synonym Symbols
CD18; TNFCR; D12S370; TNFR-RP; TNFRSF3; TNFR2-RP; LT-BETA-R; TNF-R-III
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 3
UniProt Synonym Protein Names
Lymphotoxin-beta receptor; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor type III; TNF-RIII; TNFR-III
UniProt Gene Name
LTBR
UniProt Synonym Gene Names
D12S370; TNFCR; TNFR3; TNFRSF3; TNF-RIII; TNFR-III
UniProt Entry Name
TNR3_HUMAN
NCBI Protein Information
tumor necrosis factor receptor superfamily member 3; TNF-RIII; TNFR-III; lymphotoxin B receptor; lymphotoxin-beta receptor; TNFR superfamily, member 3; tumor necrosis factor C receptor; tumor necrosis factor receptor type III; tumor necrosis factor recept

UniProt Comments for LTBR

LTBR: Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: identical protein binding; protein binding; tumor necrosis factor receptor activity; ubiquitin protein ligase binding

Biological Process: immune response; inflammatory response; multicellular organismal development; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; regulation of cell proliferation; response to lipopolysaccharide; signal transduction; tumor necrosis factor-mediated signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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