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PLEKHA1/TAPP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3905374

Pleckstrin homology domain containing A1 (PLECKHA1) binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. PLECKHA1 may recruit other proteins to the plasma membrane. [taken from the Universal Protein… More details

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Product Overview

Online Datasheet in PDF
Product Name
PLEKHA1/TAPP1, Polyclonal Antibody
Full Product Name
Rabbit anti-PLEKHA1/TAPP1 Antibody, Affinity Purified
Product Synonym Gene Name
PLEKHA1
Product Synonym Names
PH domain-containing family A member 1; pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1; pleckstrin homology domain-containing family A member 1; tandem PH domain-containing protein 1; TAPP1; TAPP-1; Pleckstrin homology domain-containing family A member 1; pleckstrin homology domain containing A1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
OMIM
AF286160 mRNA
3D Structure
ModBase 3D Structure for Q9HB21
Immunogen
Between 354 and C-terminus
Conjugation
Unconjugated

Product Categories/Family for anti-PLEKHA1/TAPP1 antibody

Applications Tested/Suitable for anti-PLEKHA1/TAPP1 antibody
Western Blot (WB)
Application Notes for anti-PLEKHA1/TAPP1 antibody
WB: 1:2000-1:10,000

Western Blot (WB) of anti-PLEKHA1/TAPP1 antibody

Detection of human PLEKHA1 by western blot. Samples: Whole cell lysate (50 ug) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-PLEKHA1 antibody MBS3905374 (lot MBS3905374-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Rabbit Anti-PLEKHA1/TAPP1 Polyclonal Antibody – Cat# MBS3905374

Other Notes

Small volumes of anti-PLEKHA1/TAPP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLEKHA1/TAPP1 purchase

MBS3905374 is an antibody targeting PLEKHA1/TAPP1. Also known as Rabbit anti-PLEKHA1/TAPP1 Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PLEKHA1/TAPP1. It may not necessarily be applicable to this product.

NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Protein Name
Pleckstrin homology domain-containing family A member 1
UniProt Synonym Protein Names
Tandem PH domain-containing protein 1; TAPP-1
UniProt Gene Name
PLEKHA1
UniProt Synonym Gene Names
TAPP1; PH domain-containing family A member 1; TAPP-1

UniProt Comments for PLEKHA1/TAPP1

PLEKHA1: Binds specifically to phosphatidylinositol 3,4- diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 10q26.13

Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus; plasma membrane

Molecular Function: PDZ domain binding; phosphatidylinositol-3,4-bisphosphate binding; protein binding

Biological Process: androgen metabolic process; B cell receptor signaling pathway; establishment of protein localization; estrogen metabolic process; Leydig cell differentiation; luteinization; multicellular organism growth; negative regulation of protein kinase B signaling cascade; palate development; phosphatidylinositol biosynthetic process; phosphoinositide 3-kinase cascade; platelet-derived growth factor receptor signaling pathway; post-embryonic development; ruffle organization; skeletal morphogenesis; spermatogenesis

Disease: Macular Degeneration, Age-related, 1
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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