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GGA1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3905459

Gamma-adaptin-related protein 1 (GGA1) is a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi… More details

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Product Overview

Online Datasheet in PDF
Product Name
GGA1, Polyclonal Antibody
Full Product Name
Rabbit anti-GGA1 Antibody, Affinity Purified
Product Gene Name
Product Synonym Names
golgi-localized, gamma ear-containing, ARF-binding protein 1; Gamma-adaptin-related protein 1; ADP-ribosylation factor binding protein 1; ADP-ribosylation factor-binding protein GGA1; gamma-adaptin related protein 1; ADP-ribosylation factor-binding protein GGA1; golgi associated, gamma adaptin ear containing, ARF binding protein 1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
72,277 Da
OMIM
606004
3D Structure
ModBase 3D Structure for Q9UJY5
Immunogen
Between 300 and 350
Conjugation
Unconjugated

Product Categories/Family for anti-GGA1 antibody

Applications Tested/Suitable for anti-GGA1 antibody
Immunoprecipitation (IP)
Application Notes for anti-GGA1 antibody
IP: 6ug/mg lysate

Immunoprecipitation (IP) of anti-GGA1 antibody

Detection of human GGA1 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-GGA1 antibody MBS3905459 (lot MBS3905459-1) used for IP at 6 ug per reaction. GGA1 was also immunoprecipitated by rabbit anti-GGA1 antibody MBS3905502. For blotting immunoprecipitated GGA1, MBS3905459 was used at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
Rabbit Anti-GGA1 Polyclonal Antibody – Cat# MBS3905459

Other Notes

Small volumes of anti-GGA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GGA1 purchase

MBS3905459 is an antibody targeting GGA1. Also known as Rabbit anti-GGA1 Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GGA1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ADP-ribosylation factor-binding protein GGA1 isoform 1
NCBI Official Synonym Full Names
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
NCBI Official Symbol
GGA1
UniProt Protein Name
ADP-ribosylation factor-binding protein GGA1
UniProt Synonym Protein Names
Gamma-adaptin-related protein 1; Golgi-localized, gamma ear-containing, ARF-binding protein 1
UniProt Gene Name
GGA1
UniProt Entry Name
GGA1_HUMAN
NCBI Protein Information
ADP-ribosylation factor-binding protein GGA1

NCBI Summary for GGA1

This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for GGA1

GGA1: Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif. Belongs to the GGA protein family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 22q13.31

Cellular Component: nucleoplasm; Golgi apparatus; clathrin adaptor complex; intracellular membrane-bound organelle; membrane; endosome membrane

Molecular Function: protein binding

Biological Process: vesicle-mediated transport; intracellular protein transport; positive regulation of protein catabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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