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PDCL Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3905630

Phosducin-like protein (PDCL) is a putative modulator of heterotrimeric G proteins. PDCL shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have… More details

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Product Overview

Online Datasheet in PDF
Product Name
PDCL, Polyclonal Antibody
Full Product Name
Rabbit anti-PDCL Antibody, Affinity Purified
Product Gene Name
Product Synonym Names
PhLP; phosducin-like protein; Phosducin-like protein; phosducin like
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
24,902 Da
OMIM
604421
3D Structure
ModBase 3D Structure for Q13371
Predicted Reactivity
Rat, Bovine
Immunogen
Between 1 and 50
Conjugation
Unconjugated

Product Categories/Family for anti-PDCL antibody

Applications Tested/Suitable for anti-PDCL antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-PDCL antibody
WB: 1:2000-1:10,000
IP: 6ug/mg lysate

Immunoprecipitation (IP) of anti-PDCL antibody

Detection of human PDCL by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-PDCL antibody MBS3905630 (lot MBS3905630-1) used for IP at 6 ug per reaction. PDCL was also immunoprecipitated by rabbit anti-PDCL antibody BL21809. For blotting immunoprecipitated PDCL, MBS3905630 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Rabbit Anti-PDCL Polyclonal Antibody – Cat# MBS3905630

Western Blot (WB) of anti-PDCL antibody

Detection of human and mouse PDCL by western blot. Samples: Whole cell lysate (50 ug) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-PDCL antibody MBS3905630 (lot MBS3905630-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
Rabbit Anti-PDCL Polyclonal Antibody, Western Blot (WB) – Cat# MBS3905630

Other Notes

Small volumes of anti-PDCL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDCL purchase

MBS3905630 is an antibody targeting PDCL. Also known as Rabbit anti-PDCL Antibody, Affinity Purified. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PDCL. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
phosducin-like protein
NCBI Official Synonym Full Names
phosducin-like
NCBI Official Symbol
PDCL
NCBI Official Synonym Symbols
PhLP
UniProt Protein Name
Phosducin-like protein
UniProt Gene Name
PDCL
UniProt Synonym Gene Names
PHLOP1; PhLP1; PHLP
UniProt Entry Name
PHLP_HUMAN
NCBI Protein Information
phosducin-like protein

NCBI Summary for PDCL

Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008]
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UniProt Comments for PDCL

PhLP: a member of the phosducin family of G-protein beta-gamma regulators. Shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins. Two splice variants have been described.

Protein type: G protein regulator, misc.

Chromosomal Location of Human Ortholog: 9q12-q13

Cellular Component: cytoplasm

Molecular Function: protein binding; receptor signaling protein activity; protein complex binding

Biological Process: protein folding; visual perception; signal transduction; regulation of G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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