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NARFL Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3905871

Small glutamine-rich tetratricopeptide repeat-containing protein beta (SGTB) is a co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96EQ0]. More details

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Product Overview

Online Datasheet in PDF
Product Name
NARFL, Polyclonal Antibody
Full Product Name
Rabbit anti-NARFL Antibody, Affinity Purified
Product Gene Name
Product Synonym Gene Name
CIAO3
Product Synonym Names
cytosolic Fe-S cluster assembly factor NARFL; NARFL; protein related to Narf; PRN; Nuclear prelamin A recognition factor-like protein; nuclear prelamin A recognition factor like; LET1L; LET1 like/JFP15; iron-only hydrogenase-like protein 1; IOP1; HPRN; NAR1; Cytosolic Fe-S cluster assembly factor NARFL; cytosolic iron-sulfur assembly component 3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
53,020 Da
Chromosome Location
Chromosome: 16; NC_000016.9 (779767..790997, complement). Location: 16p13.3
OMIM
611118
3D Structure
ModBase 3D Structure for Q9H6Q4
Predicted Reactivity
Mouse, Rat, Orangutan
Immunogen
Between 225 and 275
Conjugation
Unconjugated

Product Categories/Family for anti-NARFL antibody

Applications Tested/Suitable for anti-NARFL antibody
Immunoprecipitation (IP)
Application Notes for anti-NARFL antibody
IP: 6ug/mg lysate

Immunoprecipitation (IP) of anti-NARFL antibody

Detection of human NARFL by western blot of immunoprecipitates. Samples: Whole cell lysate (1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-NARFL antibody (MBS3905871 lot 1) used for IP at 6 ug per reaction. NARFL was also immunoprecipitated by rabbit anti-NARFL antibody MBS3905870. For blotting immunoprecipitated NARFL, MBS3905871 was used at 0.4 mg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Rabbit Anti-NARFL Polyclonal Antibody – Cat# MBS3905871

Other Notes

Small volumes of anti-NARFL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NARFL purchase

MBS3905871 is an antibody targeting NARFL. Also known as Rabbit anti-NARFL Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NARFL. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cytosolic Fe-S cluster assembly factor NARFL
NCBI Official Synonym Full Names
nuclear prelamin A recognition factor-like
NCBI Official Symbol
NARFL
NCBI Official Synonym Symbols
PRN; HPRN; IOP1; LET1L
UniProt Protein Name
Cytosolic Fe-S cluster assembly factor NARFL
UniProt Synonym Protein Names
Iron-only hydrogenase-like protein 1; IOP1; Nuclear prelamin A recognition factor-like protein; Protein related to Narf
UniProt Gene Name
NARFL
UniProt Synonym Gene Names
PRN; IOP1
UniProt Entry Name
NARFL_HUMAN
NCBI Protein Information
cytosolic Fe-S cluster assembly factor NARFL; LET1 like/JFP15; protein related to Narf; iron-only hydrogenase-like protein 1; nuclear prelamin A recognition factor-like protein

UniProt Comments for NARFL

NARFL: Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect. Belongs to the NARF family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 16p13.3

Molecular Function: 4 iron, 4 sulfur cluster binding; metal ion binding

Biological Process: oxygen homeostasis; regulation of transcription, DNA-dependent; iron-sulfur cluster assembly; response to hypoxia; hemopoietic progenitor cell differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-NARFL antibody

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