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CSN1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3907465

CSN1 is one of eight subunits (CSN1 to 8) of the highly conserved COP9 signalsome (CSN) complex originally identified as a regulator of light-mediated development in Arabidopsis. Characterization of CSN from yeast to mammals reveals a function as a modulator… More details

$250 / 0.0025 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
CSN1, Polyclonal Antibody
Full Product Name
Rabbit anti-CSN1 IHC Antibody, Affinity Purified
Product Gene Name
Product Synonym Gene Name
GPS1
Product Synonym Names
Protein MFH; COP9 signalosome complex subunit 1; SGN1; JAB1-containing signalosome subunit 1; GPS-1; G protein pathway suppressor 1; CSN1; COPS1; Signalosome subunit 1; COP9 signalosome complex subunit 1; G protein pathway suppressor 1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
250ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
55,537 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (80009763..80015346). Location: 17q25.3
OMIM
601934
3D Structure
ModBase 3D Structure for Q13098
Predicted Reactivity
Mouse, Rat, Chicken, Turkey, Bovine, Dog, Horse, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, Tasmanian devil, Crab-eating macaque, Chinese hamster, White-tufted-ear marmoset, Little brown bat, Zebra finch, Northern white-cheeked gibbon, Small-eared galago, Thirteen-lined ground squirrel, Green anole
Immunogen
Between 441 and C-terminus
Conjugation
Unconjugated

Product Categories/Family for anti-CSN1 antibody

Applications Tested/Suitable for anti-CSN1 antibody
Immunohistochemistry (IHC)
Application Notes for anti-CSN1 antibody
IHC: 1:100-1:500

Immunohistochemistry (IHC) of anti-CSN1 antibody

Detection of human CSN1 by immunohistochemistry. Sample: FFPE section of human prostate-nodular hypertrophy. Antibody: Affinity purified rabbit anti-CSN1 (Cat. No. MBS3907465) used at a dilution of 1:250. Detection: DAB
Rabbit Anti-CSN1 Polyclonal Antibody – Cat# MBS3907465

Other Notes

Small volumes of anti-CSN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CSN1 purchase

MBS3907465 is an antibody targeting CSN1. Also known as Rabbit anti-CSN1 IHC Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CSN1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
COP9 signalosome complex subunit 1 isoform 2
NCBI Official Synonym Full Names
G protein pathway suppressor 1
NCBI Official Symbol
GPS1
NCBI Official Synonym Symbols
CSN1; COPS1
UniProt Protein Name
COP9 signalosome complex subunit 1
UniProt Synonym Protein Names
G protein pathway suppressor 1; GPS-1; JAB1-containing signalosome subunit 1; Protein MFH
UniProt Gene Name
GPS1
UniProt Synonym Gene Names
COPS1; CSN1; SGN1; Signalosome subunit 1; GPS-1
UniProt Entry Name
CSN1_HUMAN
NCBI Protein Information
COP9 signalosome complex subunit 1; SGN1; GPS-1; signalosome subunit 1; COP9 signalosome subunit 1; JAB1-containing signalosome subunit 1

NCBI Summary for CSN1

This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for CSN1

COPS1: a protein that suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction. Shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells.

Protein type: G protein regulator, misc.

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: signalosome; cytoplasm; nucleus

Molecular Function: protein binding; GTPase inhibitor activity

Biological Process: cullin deneddylation; JNK cascade; cell cycle; inactivation of MAPK activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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