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USP3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3907650

Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can… More details

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Product Overview

Online Datasheet in PDF
Product Name
USP3, Polyclonal Antibody
Full Product Name
Rabbit anti-USP3 IHC Antibody, Affinity Purified
Product Gene Name
anti-USP3 antibody
Product Synonym Names
ubiquitin thioesterase 3; UBP; ubiquitin thiolesterase 3; ubiquitin carboxyl-terminal hydrolase 3; deubiquitinating enzyme 3; SIH003; ubiquitin-specific-processing protease 3; Ubiquitin carboxyl-terminal hydrolase 3; ubiquitin specific peptidase 3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
100ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
OMIM
604728
3D Structure
ModBase 3D Structure for Q9Y6I4
Predicted Reactivity
Gorilla, Chimpanzee, Naked mole rat
Immunogen
Between 470 and C-terminus
Conjugation
Unconjugated

Product Categories/Family for anti-USP3 antibody

Primary Antibodies
Applications Tested/Suitable for anti-USP3 antibody
Immunohistochemistry (IHC), Immunohistochemistry-Immunofluorescence (IHC-IF)
Application Notes for anti-USP3 antibody
IHC: 1:100-1:500
IHC-IF: 1:50-1:500

Immunohistochemistry (IHC) of anti-USP3 antibody

Detection of human USP3 by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-USP3 (Cat. No. MBS3907650) used at a dilution of 1:500. Detection: DAB
Rabbit Anti-USP3 Polyclonal Antibody – Cat# MBS3907650

Immunohistochemistry (IHC) of anti-USP3 antibody

Detection of human USP3 by immunohistochemistry. Sample: FFPE section of human pancreatic islet cell tumor. Antibody: Affinity purified rabbit anti-USP3 (Cat. No. MBS3907650) used at a dilution of 1:100. Detection: DAB
Rabbit Anti-USP3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS3907650

Immunohistochemistry (IHC) of anti-USP3 antibody

Detection of human USP3 by IHC-IF. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-USP3 (Cat. No. MBS3907650) used at a dilution of 1:100. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody Hilyte Plus 555 used at a dilution of 1:100.
Rabbit Anti-USP3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS3907650

Other Notes

Small volumes of anti-USP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for USP3 purchase

MBS3907650 is an antibody targeting USP3. Also known as Rabbit anti-USP3 IHC Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for USP3. It may not necessarily be applicable to this product.

NCBI GeneID
9960
NCBI Accession #
AAD42992.1
UniProt Primary Accession #
Q9Y6I4
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase 3
UniProt Synonym Protein Names
Deubiquitinating enzyme 3; Ubiquitin thioesterase 3; Ubiquitin-specific-processing protease 3
UniProt Gene Name
USP3
UniProt Entry Name
UBP3_HUMAN

UniProt Comments for USP3

USP3: Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin. Belongs to the peptidase C19 family. USP3 subfamily.

Protein type: Protease; Ubiquitin-specific protease; EC 3.4.19.12; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 15q22.3

Cellular Component: nuclear chromatin

Molecular Function: zinc ion binding; histone binding; cysteine-type endopeptidase activity; ubiquitin-specific protease activity; chromatin binding

Biological Process: proteasomal ubiquitin-dependent protein catabolic process; regulation of transcription, DNA-dependent; regulation of protein stability; mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; DNA repair; histone deubiquitination
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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