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Ki-67 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3907694

Ki-67 is a marker of cell proliferation detected in cells that are in G1-, S-, G2-, and M-phase of the cell cycle and absent in cells in G0. Ki-67 is detected exclusively in the nucleus, and its detection by immunohistological methods has proven to have test… More details

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Product Overview

Online Datasheet in PDF
Product Name
Ki-67, Polyclonal Antibody
Full Product Name
Rabbit anti-Ki-67 IHC Antibody, Affinity Purified
Product Gene Name
Product Synonym Gene Name
Mki67
Product Synonym Names
antigen Ki67 homolog; Ki-67; Ki67; proliferation marker protein Ki-67; antigen KI-67; antigen identified by monoclonal antibody Ki-67 homolog; D630048A14Rik; antigen KI-67 homolog; Ki-67 protein; antigen identified by monoclonal antibody Ki 67
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Liquid. Whole IgG. Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
250ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
3D Structure
ModBase 3D Structure for E9PVX6
Immunogen
Between 1875 and 1925
Conjugation
Unconjugated

Product Categories/Family for anti-Ki-67 antibody

Applications Tested/Suitable for anti-Ki-67 antibody
Immunohistochemistry (IHC)
Application Notes for anti-Ki-67 antibody
IHC: 1:100-1:500

Immunohistochemistry (IHC) of anti-Ki-67 antibody

Detection of mouse Ki-67 by immunohistochemistry. Sample: FFPE section of mouse intestine. Antibody: Affinity purified rabbit anti-mouse Ki-67 (Cat. No. MBS3907694) used at a dilution of 1:250. Detection: DAB
Rabbit Anti-Ki-67 Polyclonal Antibody – Cat# MBS3907694

Immunohistochemistry (IHC) of anti-Ki-67 antibody

Detection of mouse Ki-67 by immunohistochemistry. Sample: FFPE section of mouse peyer's patch. Antibody: Affinity purified rabbit anti-mouse Ki-67 (Cat. No. MBS3907694) used at a dilution of 1:250. Detection: DAB
Rabbit Anti-Ki-67 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS3907694

Immunohistochemistry (IHC) of anti-Ki-67 antibody

Detection of mouse Ki-67 by immunohistochemistry. Sample: FFPE section of mouse intestine. Antibody: Affinity purified rabbit anti-mouse Ki-67 (Cat. No. MBS3907694) used at a dilution of 1:250. Detection: DAB
Rabbit Anti-Ki-67 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS3907694

Immunohistochemistry (IHC) of anti-Ki-67 antibody

Detection of mouse Ki-67 by immunohistochemistry. Sample: FFPE section of mouse spleen. Antibody: Affinity purified rabbit anti-mouse Ki-67 (Cat. No. MBS3907694) used at a dilution of 1:250. Detection: DAB
Rabbit Anti-Ki-67 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS3907694

Other Notes

Small volumes of anti-Ki-67 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ki-67 purchase

MBS3907694 is an antibody targeting Ki-67. Also known as Rabbit anti-Ki-67 IHC Antibody, Affinity Purified. Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Ki-67. It may not necessarily be applicable to this product.

NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Protein Name
Proliferation marker protein Ki-67
UniProt Synonym Protein Names
Antigen identified by monoclonal antibody Ki-67 homologCurated; Antigen KI-67 homologCurated; Antigen Ki67 homologCurated
UniProt Gene Name
Mki67
UniProt Synonym Gene Names
Antigen KI-67 homologCurated; Antigen Ki67 homologCurated

UniProt Comments for Ki-67

Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (). Does not contribute to the internal structure of mitotic chromosomes (PubMed:26949251). May play a role in chromatin organization (PubMed:26949251). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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