Rabbit Anti-BRD7 Polyclonal Antibody – Cat# MBS3907930

Detection of human BRD7 by immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-BRD7 (Cat. No. MBS3907930) used at a dilution of 1:250. Detection: DAB

BRD7 Antibody – Rabbit Polyclonal

Name: BRD7 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS3907930
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3907930

Bromodomain-containing protein 7 was identified in a two-hybrid screen as an interactor of interferon regulatory factor-2 (IRF-2) and called CELTIX1. BRD7 was also identified as a binding partner of disheveled-1 (Dvl-1) and found to play a role in Wnt… More details

$250 / 0.0025 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BRD7, Polyclonal Antibody

Full Product Name

Rabbit anti-BRD7 IHC Antibody, Affinity Purified

Product Gene Name

anti-BRD7 antibody

Product Synonym Names

BP75; bromodomain-containing protein 7; CELTIX1; NAG4; protein CELTIX-1; 75 kDa bromodomain protein; Bromodomain-containing protein 7; bromodomain containing 7

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid. Whole IgG. Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide

Purity/Purification

Antigen Affinity Purified

Concentration

250ug/ml (lot specific)

Preparation and Storage

Store at 2-8 degree C
Shelf Life: 1 year from date of receipt

3D Structure

ModBase 3D Structure for Q9NPI1

Predicted Reactivity

Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon

Immunogen

Between 601 and C-terminus

Conjugation

Unconjugated

Product Categories/Family for anti-BRD7 antibody

Primary Antibodies

Applications Tested/Suitable for anti-BRD7 antibody

Immunohistochemistry (IHC)

Application Notes for anti-BRD7 antibody

IHC: 1:100-1:500

Other Notes

Small volumes of anti-BRD7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BRD7 purchase

MBS3907930 is an antibody targeting BRD7. Also known as Rabbit anti-BRD7 IHC Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BRD7. It may not necessarily be applicable to this product.

NCBI GeneID

29117

NCBI Accession #

NP_037395.2

UniProt Primary Accession #

Q9NPI1

UniProt Protein Name

Bromodomain-containing protein 7

UniProt Synonym Protein Names

75 kDa bromodomain protein; Protein CELTIX-1

Protein Family

Bromodomain-containing protein

UniProt Gene Name

BRD7

UniProt Synonym Gene Names

BP75; CELTIX1

UniProt Entry Name

BRD7_HUMAN

UniProt Comments for BRD7

BRD7: a bromodomain protein that binds dishevelled-1 (DVL1) and enhances Wnt signaling by inhibiting GSK3B. Interacts with DVL1, PTPN13, IRF2 and HNRPUL1. Associates with histones and E1B-AP5. Binds acetylated histone peptides, most notably H3 peptide acetylated at Lys14. Associates with histones and E1B-AP5. Its bromodomain is found in many chromatin-associated proteins and most known histone acetyltransferases. Inhibits G1-S progression by transcriptional regulation of molecules in the ras and Rb pathways. Plays an important role in transcriptional activation and chromatin remodeling. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription regulation; Tumor suppressor; Cell cycle regulation; Histone-binding

Chromosomal Location of Human Ortholog: 16q12

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; histone binding; p53 binding; transcription coactivator activity; transcription factor binding; transcription corepressor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; negative regulation of cell proliferation; Wnt receptor signaling pathway; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of histone acetylation; negative regulation of transcription, DNA-dependent; cell cycle

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.