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BHD Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3907943

Defects in the folliculin (FLCN) gene are the cause of Birt-Hogg-Dube syndrome (BHD) [MIM:135150]. BHD is a rare autosomal dominant genodermatosis characterized by hair follicle hamartomas (fibrofolliculomas), kidney tumors, and spontaneous pneumothorax.… More details

$250 / 0.0025 mg +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
BHD, Polyclonal Antibody
Full Product Name
Rabbit anti-BHD IHC Antibody, Affinity Purified
Product Gene Name
Product Synonym Gene Name
FLCN
Product Synonym Names
BHD skin lesion fibrofolliculoma protein; birt-Hogg-Dube syndrome protein; FLCL; folliculin; BHD; Folliculin; folliculin
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
250ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
64,473 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (17115523..17140502, complement). Location: 17p11.2
OMIM
AF517523 mRNA
3D Structure
ModBase 3D Structure for Q8NFG4
Predicted Reactivity
Gorilla, Chimpanzee
Immunogen
Between 1 and 50
Conjugation
Unconjugated

Product Categories/Family for anti-BHD antibody

Applications Tested/Suitable for anti-BHD antibody
Immunohistochemistry (IHC)
Application Notes for anti-BHD antibody
IHC: 1:100-1:500

Immunohistochemistry (IHC) of anti-BHD antibody

Detection of human BHD by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-BHD (Cat. No. MBS3907943) used at a dilution of 1:250 Detection: DAB
Rabbit Anti-BHD Polyclonal Antibody – Cat# MBS3907943

Immunohistochemistry (IHC) of anti-BHD antibody

Detection of human BHD by immunohistochemistry. Sample: FFPE section of human linitis plastica stomach cancer. Antibody: Affinity purified rabbit anti-BHD (Cat. No. MBS3907943) used at a dilution of 1:250 Detection: DAB
Rabbit Anti-BHD Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS3907943

Other Notes

Small volumes of anti-BHD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BHD purchase

MBS3907943 is an antibody targeting BHD. Also known as Rabbit anti-BHD IHC Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BHD. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
folliculin isoform 1
NCBI Official Synonym Full Names
folliculin
NCBI Official Symbol
FLCN
NCBI Official Synonym Symbols
BHD; FLCL
UniProt Protein Name
Folliculin
UniProt Synonym Protein Names
BHD skin lesion fibrofolliculoma protein; Birt-Hogg-Dube syndrome protein
UniProt Gene Name
FLCN
UniProt Synonym Gene Names
BHD
NCBI Protein Information
folliculin; birt-Hogg-Dube syndrome protein; BHD skin lesion fibrofolliculoma protein

NCBI Summary for BHD

This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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UniProt Comments for BHD

May be a tumor suppressor. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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